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Difference between revisions of "Salivary gland mucocele"
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'''Salivary gland mucocele''', also '''salivary mucocele''' and '''[[mucocele]]''', is a benign lesion of the head and neck. | |||
''Ranula'' redirects here. A ranula is a mucocele that occurs in the floor mouth.<ref name=pmid28194490>{{cite journal |authors=Kokong D, Iduh A, Chukwu I, Mugu J, Nuhu S, Augustine S |title=Ranula: Current Concept of Pathophysiologic Basis and Surgical Management Options |journal=World J Surg |volume=41 |issue=6 |pages=1476–1481 |date=June 2017 |pmid=28194490 |pmc=5422487 |doi=10.1007/s00268-017-3901-2 |url=}}</ref> | |||
==General== | |||
*Benign. | |||
*Infected [[mucocele]] = mucopyocele. | |||
*Cancer may mimic a mucocele.<ref name=pmid29231036>{{cite journal |authors=Sousa Melo SL, Lanzel E, Pagedar NA, Alhazmi D, Dahmoush L, Policeni BA, Campos MS |title=Mucoepidermoid carcinoma mimicking a mucocele (ranula) in the floor of the mouth |journal=Dentomaxillofac Radiol |volume=47 |issue=4 |pages=20170331 |date=May 2018 |pmid=29231036 |pmc=5991757 |doi=10.1259/dmfr.20170331 |url=}}</ref> | |||
==Gross== | |||
Features: | |||
*Floor of mouth lesion. | |||
===Images=== | |||
<gallery> | |||
Image: Ranula_human_09.jpg | Mucocele (ranula). (WC/Ph0t0happy) | |||
</gallery> | |||
==Microscopic== | |||
Features:<ref>URL: [http://emedicine.medscape.com/article/1076717-workup http://emedicine.medscape.com/article/1076717-workup]. Accessed on: 6 March 2012.</ref> | |||
*Granulation tissue-like and pseudocyst-like. | |||
**Granulation tissue-like: | |||
***Fibroblasts. | |||
***Small caliber blood vessels. | |||
***Histocytes. | |||
***Neutrophils. | |||
**Pseudocyst: | |||
***No epithelial lining. | |||
***Poorly circumscribed. | |||
*Pale pink extracellular material (mucous) - '''key feature'''. | |||
*+/-[[Granuloma]]s.<ref name=pmid7251405>{{Cite journal | last1 = Seifert | first1 = G. | last2 = Donath | first2 = K. | last3 = von Gumberz | first3 = C. | title = [Mucoceles of the minor salivary glands. Extravasation mucoceles (mucus granulomas) and retention mucoceles (mucus retention cysts) (author's transl)]. | journal = HNO | volume = 29 | issue = 6 | pages = 179-91 | month = Jun | year = 1981 | doi = | PMID = 7251405 }}</ref> | |||
DDx: | |||
*[[Granulation tissue]]. | |||
*[[Signet ring cell carcinoma]] - muciphages may mimic signet ring cells. | |||
===Images=== | |||
<gallery> | |||
Image:Mucocele_of_lower_lip_%281%29.JPG | Mucocele - low mag. (WC/KGH) | |||
Image:Mucocele_of_lower_lip_%282%29.JPG | Mucocele - high mag. (WC/KGH) | |||
Image:Mucocele_-_low_mag.jpg | Mucocele - low mag. (WC/Nephron) | |||
Image:Mucocele_-_high_mag.jpg | Mucocele - high mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://dermatlas.med.jhmi.edu/derm/indexDisplay.cfm?ImageID=292590975 Mucocele (dermatlas.med.jhmi.edu)]. | |||
==Sign out== | |||
<pre> | |||
LESION, LEFT LOWER LIP, EXCISION: | |||
- BENIGN MUCOCELE. | |||
</pre> | |||
===Micro=== | |||
The sections show a stratified squamous epithelium with a thin layer of parakeratosis, | |||
minor salivary glands, and a well-circumscribed cystic lesion. | |||
The cystic lesion has a mildly fibrotic appearing wall, is lined by histiocytes intermixed with rare lymphocytes, and contains mucous and macrophages. No significant nuclear atypia is identified. Mitotic activity is not readily apparent. | |||
==See also== | |||
*[[Salivary gland]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||