Difference between revisions of "SALL4"

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{{ Infobox immunostain
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| Pattern    = nuclear stain
| Positive  = [[germ cell tumours]]
| Negative  =
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}}
'''SALL4''' is an [[immunostain]] that marks [[germ cell tumours]].<ref name=pmid24525512>{{Cite journal  | last1 = Miettinen | first1 = M. | last2 = Wang | first2 = Z. | last3 = McCue | first3 = PA. | last4 = Sarlomo-Rikala | first4 = M. | last5 = Rys | first5 = J. | last6 = Biernat | first6 = W. | last7 = Lasota | first7 = J. | last8 = Lee | first8 = YS. | title = SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 3 | pages = 410-20 | month = Mar | year = 2014 | doi = 10.1097/PAS.0000000000000116 | PMID = 24525512 }}</ref>
'''SALL4''' is an [[immunostain]] that marks [[germ cell tumours]].<ref name=pmid24525512>{{Cite journal  | last1 = Miettinen | first1 = M. | last2 = Wang | first2 = Z. | last3 = McCue | first3 = PA. | last4 = Sarlomo-Rikala | first4 = M. | last5 = Rys | first5 = J. | last6 = Biernat | first6 = W. | last7 = Lasota | first7 = J. | last8 = Lee | first8 = YS. | title = SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases. | journal = Am J Surg Pathol | volume = 38 | issue = 3 | pages = 410-20 | month = Mar | year = 2014 | doi = 10.1097/PAS.0000000000000116 | PMID = 24525512 }}</ref>
==Use==
*[[Germ cell tumour]] versus [[sex cord-stromal tumour]].<ref name=pmid25025364>{{cite journal |author=Amin MB, Epstein JI, Ulbright TM, ''et al.'' |title=Best practices recommendations in the application of immunohistochemistry in urologic pathology: report from the international society of urological pathology consensus conference |journal=Am. J. Surg. Pathol. |volume=38 |issue=8 |pages=1017–22 |year=2014 |month=August |pmid=25025364 |doi=10.1097/PAS.0000000000000254 |url=}}</ref>
===Images===
*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041084/figure/F2/ SALL4 in GCTs (nih.gov)].<ref name=pmid24525512/>


==See also==
==See also==
*[[Immunohistochemistry]].
*[[Immunohistochemistry]].
*[[OCT3/4]].


==References==
==References==

Latest revision as of 20:30, 5 March 2021

SALL4 is an immunostain that marks germ cell tumours.[1]

SALL4
Immunostain in short
Normal staining pattern nuclear stain
Positive germ cell tumours

Use

Images

See also

References

  1. 1.0 1.1 Miettinen, M.; Wang, Z.; McCue, PA.; Sarlomo-Rikala, M.; Rys, J.; Biernat, W.; Lasota, J.; Lee, YS. (Mar 2014). "SALL4 expression in germ cell and non-germ cell tumors: a systematic immunohistochemical study of 3215 cases.". Am J Surg Pathol 38 (3): 410-20. doi:10.1097/PAS.0000000000000116. PMID 24525512.
  2. Amin MB, Epstein JI, Ulbright TM, et al. (August 2014). "Best practices recommendations in the application of immunohistochemistry in urologic pathology: report from the international society of urological pathology consensus conference". Am. J. Surg. Pathol. 38 (8): 1017–22. doi:10.1097/PAS.0000000000000254. PMID 25025364.