Difference between revisions of "S-100"
Jump to navigation
Jump to search
| Line 5: | Line 5: | ||
==Positive== | ==Positive== | ||
*Nerves. | *Nerves. | ||
*[[Schwannoma]]. | |||
*Mature adipose tissue. | *Mature adipose tissue. | ||
*Interdigitating dendritic cells.<ref name=pmid19466261>{{Cite journal | last1 = Mesquita | first1 = RA. | last2 = de Araújo | first2 = VC. | last3 = Paes | first3 = RA. | last4 = Nunes | first4 = FD. | last5 = de Souza | first5 = SC. | title = Immunohistochemical analysis for CD21, CD35, Caldesmon and S100 protein on dendritic cells types in oral lymphomas. | journal = J Appl Oral Sci | volume = 17 | issue = 3 | pages = 248-53 | month = | year = | doi = | PMID = 19466261 }} | *Interdigitating dendritic cells.<ref name=pmid19466261>{{Cite journal | last1 = Mesquita | first1 = RA. | last2 = de Araújo | first2 = VC. | last3 = Paes | first3 = RA. | last4 = Nunes | first4 = FD. | last5 = de Souza | first5 = SC. | title = Immunohistochemical analysis for CD21, CD35, Caldesmon and S100 protein on dendritic cells types in oral lymphomas. | journal = J Appl Oral Sci | volume = 17 | issue = 3 | pages = 248-53 | month = | year = | doi = | PMID = 19466261 }} | ||
| Line 10: | Line 11: | ||
*[[Langerhans cell histiocytosis]]. | *[[Langerhans cell histiocytosis]]. | ||
*[[Rosai-Dorfman disease]]. | *[[Rosai-Dorfman disease]]. | ||
*[[Chordoma]] - also keratin positive ([[AE1/AE3]], [[CK19]], [[CAM5.2]]).<ref name=pmid24296480>{{Cite journal | last1 = Shen | first1 = J. | last2 = Shi | first2 = Q. | last3 = Lu | first3 = J. | last4 = Wang | first4 = DL. | last5 = Zou | first5 = TM. | last6 = Yang | first6 = HL. | last7 = Zhu | first7 = GQ. | title = Histological study of chordoma origin from fetal notochordal cell rests. | journal = Spine (Phila Pa 1976) | volume = 38 | issue = 25 | pages = 2165-70 | month = Dec | year = 2013 | doi = 10.1097/BRS.0000000000000010 | PMID = 24296480 }}</ref> | |||
*[[Chordoma]] - also keratin positive (AE1/AE3, CK19, CAM5.2).<ref name=pmid24296480>{{Cite journal | last1 = Shen | first1 = J. | last2 = Shi | first2 = Q. | last3 = Lu | first3 = J. | last4 = Wang | first4 = DL. | last5 = Zou | first5 = TM. | last6 = Yang | first6 = HL. | last7 = Zhu | first7 = GQ. | title = Histological study of chordoma origin from fetal notochordal cell rests. | journal = Spine (Phila Pa 1976) | volume = 38 | issue = 25 | pages = 2165-70 | month = Dec | year = 2013 | doi = 10.1097/BRS.0000000000000010 | PMID = 24296480 }}</ref> | *[[Granular cell tumour]]. | ||
===Malignant tumours=== | ===Malignant tumours=== | ||
Revision as of 22:17, 31 July 2016
.jpg)
S-100 staining in a MASC.
S-100, also S100, is a commonly used immunostain. It marks nerves.
Positive
- Nerves.
- Schwannoma.
- Mature adipose tissue.
- Interdigitating dendritic cells.[1]
- Langerhans cell histiocytosis.
- Rosai-Dorfman disease.
- Chordoma - also keratin positive (AE1/AE3, CK19, CAM5.2).[2]
- Granular cell tumour.
Malignant tumours
- Malignant melanoma - almost 100% sensitive.
- Malignant peripheral nerve sheath tumour.
- Clear cell sarcoma.
See also
References
- ↑ Mesquita, RA.; de Araújo, VC.; Paes, RA.; Nunes, FD.; de Souza, SC.. "Immunohistochemical analysis for CD21, CD35, Caldesmon and S100 protein on dendritic cells types in oral lymphomas.". J Appl Oral Sci 17 (3): 248-53. PMID 19466261.
- ↑ Shen, J.; Shi, Q.; Lu, J.; Wang, DL.; Zou, TM.; Yang, HL.; Zhu, GQ. (Dec 2013). "Histological study of chordoma origin from fetal notochordal cell rests.". Spine (Phila Pa 1976) 38 (25): 2165-70. doi:10.1097/BRS.0000000000000010. PMID 24296480.