Difference between revisions of "Rheumatoid lung nodule"
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'''Rheumatoid lung nodule''', also '''rheumatoid nodule of the lung''', is an uncommon benign lung lesion associated with [[rheumatoid arthritis]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = mixed inflammatory infiltrate, +/-[[giant cells]], no micro-organisms | |||
| Subtypes = | |||
| LMDDx = necrotic pulmonary nodules in [[Crohn's disease]], [[infectious pneumonia]], [[amyloidosis]] of lung | |||
| Stains = ZN -ve, GMS -ve | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[lung]] - see ''[[medical lung diseases]]'' | |||
| Assdx = [[rheumatoid arthritis]] | |||
| Syndromes = | |||
| Clinicalhx = +/-hx of rheumatoid arthritis | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = upper lung fields, peripheral, round, +/-cavitation | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = only lung lesions - esp. malignancy | |||
| Tx = | |||
}} | |||
'''Rheumatoid lung nodule''', also '''rheumatoid nodule of the lung''' and '''pulmonary rheumatoid nodule''', is an uncommon benign lung lesion associated with [[rheumatoid arthritis]]. | |||
''Rheumatoid lung disease'' redirects here. ''[[Rheumatoid pleuritis]]'' is dealt with separately. | |||
==General== | ==General== | ||
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*Mixed inflammatory infiltrate. | *Mixed inflammatory infiltrate. | ||
*+/-[[Giant cells]]. | *+/-[[Giant cells]]. | ||
*No micro-organisms. | |||
Dx: | Dx: | ||
*Necrotic pulmonary nodule in [[Crohn's disease]]. | *Necrotic pulmonary nodule in [[Crohn's disease]]. | ||
*[[Infectious pneumonia]]. | *[[Infectious pneumonia]]. | ||
*[[Amyloidosis]]<ref name=pmid17037396>{{cite journal |authors=Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H |title=Nodular pulmonary amyloidosis |journal=Jpn J Thorac Cardiovasc Surg |volume=54 |issue=9 |pages=399–401 |date=September 2006 |pmid=17037396 |doi=10.1007/s11748-006-0015-4 |url=}}</ref> - reported in the context with rheumatoid arthritis.<ref name=pmid17332981>{{cite journal |authors=Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH |title=Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis |journal=Clin Rheumatol |volume=26 |issue=10 |pages=1797–8 |date=October 2007 |pmid=17332981 |doi=10.1007/s10067-007-0552-y |url=}}</ref> | |||
===Images=== | ===Images=== | ||
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==Stains== | ==Stains== | ||
*[[ZN stain]] -ve for | *[[ZN stain]] -ve for AFB. | ||
*[[GMS stain]] -ve for [[fungal organisms]]. | *[[GMS stain]] -ve for [[fungal organisms]]. | ||
*[[Congo red]] -ve. | |||
==See also== | ==See also== |
Latest revision as of 16:36, 3 March 2022
Rheumatoid lung nodule, also rheumatoid nodule of the lung and pulmonary rheumatoid nodule, is an uncommon benign lung lesion associated with rheumatoid arthritis.
Rheumatoid lung nodule | |
---|---|
Diagnosis in short | |
| |
LM | mixed inflammatory infiltrate, +/-giant cells, no micro-organisms |
LM DDx | necrotic pulmonary nodules in Crohn's disease, infectious pneumonia, amyloidosis of lung |
Stains | ZN -ve, GMS -ve |
Site | lung - see medical lung diseases |
| |
Associated Dx | rheumatoid arthritis |
Clinical history | +/-hx of rheumatoid arthritis |
Prevalence | uncommon |
Radiology | upper lung fields, peripheral, round, +/-cavitation |
Clin. DDx | only lung lesions - esp. malignancy |
Rheumatoid lung disease redirects here. Rheumatoid pleuritis is dealt with separately.
General
- Rare.[1]
Common associations:[1]
- Male.
- RF +ve.
- Skin nodules - see rheumatoid nodule.
Gross/radiology
Features:[1]
- Usually upper lung fields, peripheral and round.
- +/-Cavitation (~50% of cases).
Microscopic
Features:[2]
- Mixed inflammatory infiltrate.
- +/-Giant cells.
- No micro-organisms.
Dx:
- Necrotic pulmonary nodule in Crohn's disease.
- Infectious pneumonia.
- Amyloidosis[3] - reported in the context with rheumatoid arthritis.[4]
Images
www:
Stains
- ZN stain -ve for AFB.
- GMS stain -ve for fungal organisms.
- Congo red -ve.
See also
References
- ↑ 1.0 1.1 1.2 Gómez Herrero, H.; Arraiza Sarasa, M.; Rubio Marco, I.; García de Eulate Martín-Moro, I.. "Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases.". Reumatol Clin 8 (4): 212-5. doi:10.1016/j.reuma.2011.09.004. PMID 22265461.
- ↑ 2.0 2.1 2.2 Chhakchhuak, CL.; Khosravi, M.; Lohr, KM. (2013). "Role of (18)F-FDG PET Scan in Rheumatoid Lung Nodule: Case Report and Review of the Literature.". Case Rep Rheumatol 2013: 621340. doi:10.1155/2013/621340. PMID 23984160.
- ↑ Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H (September 2006). "Nodular pulmonary amyloidosis". Jpn J Thorac Cardiovasc Surg 54 (9): 399–401. doi:10.1007/s11748-006-0015-4. PMID 17037396.
- ↑ Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH (October 2007). "Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis". Clin Rheumatol 26 (10): 1797–8. doi:10.1007/s10067-007-0552-y. PMID 17332981.