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Difference between revisions of "Rheumatoid lung nodule"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = mixed inflammatory infiltrate, +/-[[giant cells]], no micro-organisms | |||
| Subtypes = | |||
| LMDDx = necrotic pulmonary nodules in [[Crohn's disease]], [[infectious pneumonia]], [[amyloidosis]] of lung | |||
| Stains = ZN -ve, GMS -ve | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[lung]] - see ''[[medical lung diseases]]'' | |||
| Assdx = [[rheumatoid arthritis]] | |||
| Syndromes = | |||
| Clinicalhx = +/-hx of rheumatoid arthritis | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = upper lung fields, peripheral, round, +/-cavitation | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = only lung lesions - esp. malignancy | |||
| Tx = | |||
}} | |||
'''Rheumatoid lung nodule''', also '''rheumatoid nodule of the lung''' and '''pulmonary rheumatoid nodule''', is an uncommon benign lung lesion associated with [[rheumatoid arthritis]]. | |||
''Rheumatoid lung disease'' redirects here. ''[[Rheumatoid pleuritis]]'' is dealt with separately. | |||
==General== | |||
*Rare.<ref name=pmid22265461>{{Cite journal | last1 = Gómez Herrero | first1 = H. | last2 = Arraiza Sarasa | first2 = M. | last3 = Rubio Marco | first3 = I. | last4 = García de Eulate Martín-Moro | first4 = I. | title = Pulmonary rheumatoid nodules: presentation, methods, diagnosis and progression in reference to 5 cases. | journal = Reumatol Clin | volume = 8 | issue = 4 | pages = 212-5 | month = | year = | doi = 10.1016/j.reuma.2011.09.004 | PMID = 22265461 }}</ref> | |||
Common associations:<ref name=pmid22265461/> | |||
*Male. | |||
*RF +ve. | |||
*Skin nodules - see ''[[rheumatoid nodule]]''. | |||
==Gross/radiology== | |||
Features:<ref name=pmid22265461/> | |||
*Usually upper lung fields, peripheral and round. | |||
*+/-Cavitation (~50% of cases). | |||
==Microscopic== | |||
Features:<ref name=pmid23984160/> | |||
*Mixed inflammatory infiltrate. | |||
*+/-[[Giant cells]]. | |||
*No micro-organisms. | |||
Dx: | |||
*Necrotic pulmonary nodule in [[Crohn's disease]]. | |||
*[[Infectious pneumonia]]. | |||
*[[Amyloidosis]]<ref name=pmid17037396>{{cite journal |authors=Tokunaga T, Takeda S, Sawabata N, Inoue M, Maeda H |title=Nodular pulmonary amyloidosis |journal=Jpn J Thorac Cardiovasc Surg |volume=54 |issue=9 |pages=399–401 |date=September 2006 |pmid=17037396 |doi=10.1007/s11748-006-0015-4 |url=}}</ref> - reported in the context with rheumatoid arthritis.<ref name=pmid17332981>{{cite journal |authors=Calatayud J, Candelas G, Gómez A, Morado C, Trancho FH |title=Nodular pulmonary amyloidosis in a patient with rheumatoid arthritis |journal=Clin Rheumatol |volume=26 |issue=10 |pages=1797–8 |date=October 2007 |pmid=17332981 |doi=10.1007/s10067-007-0552-y |url=}}</ref> | |||
===Images=== | |||
www: | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741933/figure/fig3/ RLN (nih.gov)].<ref name=pmid23984160/> | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741933/figure/fig4/ RLN (nih.gov)].<ref name=pmid23984160>{{Cite journal | last1 = Chhakchhuak | first1 = CL. | last2 = Khosravi | first2 = M. | last3 = Lohr | first3 = KM. | title = Role of (18)F-FDG PET Scan in Rheumatoid Lung Nodule: Case Report and Review of the Literature. | journal = Case Rep Rheumatol | volume = 2013 | issue = | pages = 621340 | month = | year = 2013 | doi = 10.1155/2013/621340 | PMID = 23984160 }}</ref> | |||
==Stains== | |||
*[[ZN stain]] -ve for AFB. | |||
*[[GMS stain]] -ve for [[fungal organisms]]. | |||
*[[Congo red]] -ve. | |||
==See also== | |||
*[[Medical lung disease]]. | |||
*[[Rheumatoid nodule]]. | |||
*[[Rheumatoid arthritis]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | |||