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Difference between revisions of "Rhabdomyosarcoma"
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==Microscopic== | ==Microscopic== | ||
===Alveolar rhabdomyosarcoma=== | ===Alveolar rhabdomyosarcoma=== | ||
Features:<ref name=PST14feb11 | Features:<ref name=PST14feb11/> | ||
*Alveolus-like pattern -- '''key low-power feature'''. | *Alveolus-like pattern -- '''key low-power feature'''. | ||
**Fibrous septae lined by tumour cells. | **Fibrous septae lined by tumour cells. | ||
| Line 107: | Line 107: | ||
===Embryonal rhabdomyosarcoma=== | ===Embryonal rhabdomyosarcoma=== | ||
Features:<ref name=PST14feb11 | Features:<ref name=PST14feb11/> | ||
*Randomly arranged small cells. | *Randomly arranged small cells. | ||
*[[Myxoid]] matrix. | *[[Myxoid]] matrix. | ||
| Line 175: | Line 175: | ||
===Subtyping via IHC=== | ===Subtyping via IHC=== | ||
PST proposes<ref name=PST14feb11 | PST proposes<ref name=PST14feb11/> the following (presumably based on Makawitz et al.<ref name=pmid18788888>{{cite journal |author=Makawita S, Ho M, Durbin AD, Thorner PS, Malkin D, Somers GR |title=Expression of insulin-like growth factor pathway proteins in rhabdomyosarcoma: IGF-2 expression is associated with translocation-negative tumors |journal=Pediatr. Dev. Pathol. |volume=12 |issue=2 |pages=127–35 |year=2009 |pmid=18788888 |doi=10.2350/08-05-0477.1 |url=}}</ref>): | ||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | {| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | ||
| '''IHC''' | | '''IHC''' | ||