Retroperitoneal fibrosis

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Retroperitoneal fibrosis is a rare thingy urologists and rheumatologists dealt with.

General

Treatment:

  • Immunosuppression.

Microscopic

Features:[3][1]

  • Fibrous tissue (pink background) with inflammatory cells (plasma cells, benign lymphocytes and eosinophils).

Note:

  • Entrapped adipocytes (white open spaces) are common.

Images

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A. KIDNEY, RIGHT, RADICAL NEPHRECTOMY:
- SEVERE PYELONEPHRITIS, CHRONIC ACTIVE.
- EXTENSIVE TOTAL SCLEROSIS OF GLOMERULI AND INTERSTITIAL FIBROSIS (END-STAGE KIDNEY).
- PERIRENAL FAT WITH FOCI OF FAT NECROSIS, FIBROSIS AND A MIXED INFLAMMATORY
  INFILTRATE WITH PLASMA CELLS.
- NEGATIVE FOR MALIGNANCY.

B. SOFT TISSUE, RETROPERITONEUM, BIOPSY:
- FIBROTIC SOFT TISSUE WITH A MINIMAL FOCAL LYMPHOCYTIC INFILTRATE.
- NEGATIVE FOR MALIGNANCY.

See also

References

  1. 1.0 1.1 Rodríguez Jornet, A.; Andreu Navarro, FJ.; Orellana Fernández, R.; Ibeas López, J.; García García, M. (2009). "[Idiopathic retroperitoneal fibrosis: clinico-pathological characteristics].". Nefrologia 29 (4): 298-303. doi:10.3265/Nefrologia.2009.29.4.5344.en.full. PMID 19668300.
  2. Kamisawa, T.; Okamoto, A. (Jul 2008). "IgG4-related sclerosing disease.". World J Gastroenterol 14 (25): 3948-55. PMID 18609677.
  3. URL: http://www.mypacs.net/cases/RETROPERITONEAL-FIBROSIS-17484372.html. Accessed on: 20 October 2011.