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Renal tumours with eosinophilic cytoplasm (view source)
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'''[[Renal tumours]] with eosinophilic cytoplasm''' are relatively common and have a differential diagnosis. | [[Image:Eosinophilic variant of chromophobe renal cell carcinoma -- very high mag.jpg|thumb|right|A renal tumour with an eosinophilic cytoplasm ([[chromophobe RCC]]). (WC/Nephron)]] | ||
'''[[Renal tumours]] with eosinophilic cytoplasm''', also '''eosinophilic renal tumours''' and '''kidney tumours with eosinophilic cytoplasm''', are relatively common and have a [[differential diagnosis]]. | |||
==Common== | ==Common== | ||
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==Less common== | ==Less common== | ||
*[[Clear cell renal cell carcinoma]], eosinophilic variant - often high-grade/aggressive tumours. | *[[Clear cell renal cell carcinoma]], eosinophilic variant<ref name=pmid1780705>{{Cite journal | last1 = Engel | first1 = U. | last2 = Horn | first2 = T. | title = Eosinophilic renal cell tumours. A study on tumour heterogeneity with special emphasis on oncocytes. | journal = Scand J Urol Nephrol | volume = 25 | issue = 4 | pages = 297-301 | month = | year = 1991 | doi = | PMID = 1780705 }}</ref> - often high-grade/aggressive tumours. | ||
*[[Papillary renal cell carcinoma]], | *[[Papillary renal cell carcinoma]], oncocytic variant.<ref name=pmid23826421>{{Cite journal | last1 = Xia | first1 = QY. | last2 = Rao | first2 = Q. | last3 = Shen | first3 = Q. | last4 = Shi | first4 = SS. | last5 = Li | first5 = L. | last6 = Liu | first6 = B. | last7 = Zhang | first7 = J. | last8 = Wang | first8 = YF. | last9 = Shi | first9 = QL. | title = Oncocytic papillary renal cell carcinoma: a clinicopathological study emphasizing distinct morphology, extended immunohistochemical profile and cytogenetic features. | journal = Int J Clin Exp Pathol | volume = 6 | issue = 7 | pages = 1392-9 | month = | year = 2013 | doi = | PMID = 23826421 }}</ref> | ||
==Rare stuff== | ==Rare stuff== | ||
*[[Angiomyolipoma]]. | [[Image:Eosinophilic, solid and cystic renal cell carcinoma - solid -- very high mag.jpg|thumb|right|[[ESC-RCC]], an evolving entity with eosinophilic cytoplasm. [[H&E stain]]. (WC)]] | ||
[[Image:Low grade oncocytic renal tumour -- very high mag.jpg|thumb|right|Low-grade oncocytic renal tumour, an evolving entity with eosinophilic cytoplasm. [[H&E stain]].]] | |||
*[[Angiomyolipoma]], epithelioid. | |||
*[[Xp11.2 translocation carcinoma]]. | *[[Xp11.2 translocation carcinoma]]. | ||
*[[Hereditary leiomyomatosis renal cell carcinoma syndrome associated renal cell carcinoma]].<ref name=pmid25357116>{{Cite journal | last1 = Kryvenko | first1 = ON. | last2 = Jorda | first2 = M. | last3 = Argani | first3 = P. | last4 = Epstein | first4 = JI. | title = Diagnostic approach to eosinophilic renal neoplasms. | journal = Arch Pathol Lab Med | volume = 138 | issue = 11 | pages = 1531-41 | month = Nov | year = 2014 | doi = 10.5858/arpa.2013-0653-RA | PMID = 25357116 }}</ref> | |||
*[[Tubulocystic carcinoma]].<ref name=pmid25357116/> | |||
*[[Acquired cystic disease-associated renal cell carcinoma]].<ref name=pmid25357116/> | |||
*[[Renal hybrid oncocytic/chromophobe tumour]].<ref name=pmid25357116/> | |||
*[[Renal oncocytosis]]. | |||
*[[Unclassified renal cell carcinoma]]. | |||
*[[Juxtaglomerular cell tumour]]. | |||
*[[Succinate dehydrogenase-deficient renal cell carcinoma]]. | |||
*[[Eosinophilic solid and cystic renal cell carcinoma]].<ref name=pmid26414221>{{Cite journal | last1 = Trpkov | first1 = K. | last2 = Hes | first2 = O. | last3 = Bonert | first3 = M. | last4 = Lopez | first4 = JI. | last5 = Bonsib | first5 = SM. | last6 = Nesi | first6 = G. | last7 = Comperat | first7 = E. | last8 = Sibony | first8 = M. | last9 = Berney | first9 = DM. | title = Eosinophilic, Solid, and Cystic Renal Cell Carcinoma: Clinicopathologic Study of 16 Unique, Sporadic Neoplasms Occurring in Women. | journal = Am J Surg Pathol | volume = | issue = | pages = | month = Sep | year = 2015 | doi = 10.1097/PAS.0000000000000508 | PMID = 26414221 }}</ref> | |||
*[[ALK translocation renal cell carcinoma]].<ref name=ref27554841 >{{Cite journal | last1 = Jeanneau | first1 = M. | last2 = Gregoire | first2 = V. | last3 = Desplechain | first3 = C. | last4 = Escande | first4 = F. | last5 = Tica | first5 = DP. | last6 = Aubert | first6 = S. | last7 = Leroy | first7 = X. | title = ALK rearrangements-associated renal cell carcinoma (RCC) with unique pathological features in an adult. | journal = Pathol Res Pract | volume = 212 | issue = 11 | pages = 1064-1066 | month = Nov | year = 2016 | doi = 10.1016/j.prp.2016.07.015 | PMID = 27554841 }}</ref> | |||
===Proposed entities=== | |||
*[[Follicular thyroid-like renal cell carcinoma]].<ref name=pmid25357116/> | |||
*[[Eosinophilic vacuolated tumour]] - previously ''high-grade oncocytic renal tumour''. | |||
*[[Papillary renal neoplasm with reverse polarity]] (PRNRP).<ref name=pmid31135486>{{cite journal |authors=Al-Obaidy KI, Eble JN, Cheng L, Williamson SR, Sakr WA, Gupta N, Idrees MT, Grignon DJ |title=Papillary Renal Neoplasm With Reverse Polarity: A Morphologic, Immunohistochemical, and Molecular Study |journal=Am J Surg Pathol |volume=43 |issue=8 |pages=1099–1111 |date=August 2019 |pmid=31135486 |doi=10.1097/PAS.0000000000001288 |url=}}</ref> | |||
*[[Low-grade oncocytic renal tumour]] (renal oncocytic tumour that is CD117 negative and CK7 positive). | |||
==See also== | |||
*[[Clear cells in the kidney]]. | |||
== | ==References== | ||
{{Reflist|1}} | |||
==External links== | ==External links== | ||