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Difference between revisions of "Renal mucinous tubular and spindle cell carcinoma"
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Renal mucinous tubular and spindle cell carcinoma (view source)
Revision as of 20:08, 20 December 2019
, 20:08, 20 December 2019→IHC: fix ref
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Renal mucinous tubular and spindle cell carcinoma -- high mag.jpg | | Image = Renal mucinous tubular and spindle cell carcinoma - 2 -- high mag.jpg | ||
| Width = | | Width = | ||
| Caption = Renal mucinous tubular and spindle cell carcinoma. [[H&E stain]]. | | Caption = Renal mucinous tubular and spindle cell carcinoma. [[H&E stain]]. | ||
| Line 46: | Line 46: | ||
*Greyish-yellow or tan-yellow. | *Greyish-yellow or tan-yellow. | ||
*Well-circumscribed. | *Well-circumscribed. | ||
Note: | |||
*Imaging characteristics overlap with [[papillary renal cell carcinoma]].<ref name=pmid25395040/> | |||
==Microscopic== | ==Microscopic== | ||
| Line 65: | Line 68: | ||
===Images=== | ===Images=== | ||
====Case 1==== | |||
<gallery> | |||
Image: Renal mucinous tubular and spindle cell carcinoma - 2 -- very low mag.jpg | RMTSCC - very low mag. | |||
Image: Renal mucinous tubular and spindle cell carcinoma - 2 -- low mag.jpg | RMTSCC - low mag. | |||
Image: Renal mucinous tubular and spindle cell carcinoma - 2 -- intermed mag.jpg | RMTSCC - intermed. mag. | |||
Image: Renal mucinous tubular and spindle cell carcinoma - 2 -- high mag.jpg | RMTSCC - high mag. | |||
Image: Renal mucinous tubular and spindle cell carcinoma - 2 -- very high mag.jpg | RMTSCC - very high mag. | |||
Image: Renal mucinous tubular and spindle cell carcinoma - 2 alt -- very high mag.jpg | RMTSCC - very high mag. | |||
</gallery> | |||
====Case 2==== | |||
<gallery> | <gallery> | ||
Image: Renal mucinous tubular and spindle cell carcinoma -- low mag.jpg | RMTSCC - low mag. | Image: Renal mucinous tubular and spindle cell carcinoma -- low mag.jpg | RMTSCC - low mag. | ||
| Line 91: | Line 104: | ||
Others: | Others: | ||
* | *[[PAX8]] +ve. | ||
*CAM5.2 +ve. | *[[CAM5.2]] +ve. | ||
*p63 -ve. | *[[p63]] -ve. | ||
*CK20 -ve.<ref name=pmid17058608>{{Cite journal | last1 = Arias | first1 = LF. | last2 = Blanco | first2 = J. | last3 = Hernández | first3 = S. | last4 = Bocardo | first4 = G. | last5 = González | first5 = L. | title = [Immunohistochemical profile and clinical features of mucinous tubular and spindle renal cell carcinoma]. | journal = Actas Urol Esp | volume = 30 | issue = 7 | pages = 649-54 | month = | year = | doi = | PMID = 17058608 }}</ref> | *[[CK20]] -ve.<ref name=pmid17058608>{{Cite journal | last1 = Arias | first1 = LF. | last2 = Blanco | first2 = J. | last3 = Hernández | first3 = S. | last4 = Bocardo | first4 = G. | last5 = González | first5 = L. | title = [Immunohistochemical profile and clinical features of mucinous tubular and spindle renal cell carcinoma]. | journal = Actas Urol Esp | volume = 30 | issue = 7 | pages = 649-54 | month = | year = | doi = | PMID = 17058608 }}</ref> | ||
*[[CD57]] +ve.<ref name=pmid18459456>{{Cite journal | last1 = Okoń | first1 = K. | last2 = Klimkowska | first2 = A. | last3 = Pawelec | first3 = A. | last4 = Dobrowolski | first4 = Z. | last5 = Kohla | first5 = Z. | last6 = Stachura | first6 = J. | title = Immunophenotype and cytogenetics of mucinous tubular and spindle cell carcinoma of the kidney. | journal = Pol J Pathol | volume = 58 | issue = 4 | pages = 227-33 | month = | year = 2007 | doi = | PMID = 18459456 }}</ref><ref name=pmid14989744>{{Cite journal | last1 = Kuroda | first1 = N. | last2 = Nakamura | first2 = S. | last3 = Miyazaki | first3 = E. | last4 = Hayashi | first4 = Y. | last5 = Taguchi | first5 = T. | last6 = Hiroi | first6 = M. | last7 = Yamasaki | first7 = Y. | last8 = Shuin | first8 = T. | last9 = Enzan | first9 = H. | title = Low-grade tubular-mucinous renal neoplasm with neuroendocrine differentiation: a histological, immunohistochemical and ultrastructural study. | journal = Pathol Int | volume = 54 | issue = 3 | pages = 201-7 | month = Mar | year = 2004 | doi = 10.1111/j.1440-1827.2004.01608.x | PMID = 14989744 }}</ref> | |||
*CK19 +ve.<ref name=pmid14989744/> | |||
Note: | Note: | ||
*Immunophenotype overlaps with [[papillary renal cell carcinoma]].<ref name= | *Immunophenotype overlaps with [[papillary renal cell carcinoma]].<ref name=pmid16330937>{{Cite journal | last1 = Paner | first1 = GP. | last2 = Srigley | first2 = JR. | last3 = Radhakrishnan | first3 = A. | last4 = Cohen | first4 = C. | last5 = Skinnider | first5 = BF. | last6 = Tickoo | first6 = SK. | last7 = Young | first7 = AN. | last8 = Amin | first8 = MB. | title = Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic caution. | journal = Am J Surg Pathol | volume = 30 | issue = 1 | pages = 13-9 | month = Jan | year = 2006 | doi = | PMID = 16330937 }}</ref> | ||
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