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Difference between revisions of "Renal cell carcinoma with fibromyomatous stroma"
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Renal cell carcinoma with fibromyomatous stroma (view source)
Revision as of 03:21, 20 March 2024
, 20 Marchno edit summary
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==Microscopic== | ==Microscopic== | ||
Features: | Features:<ref name=pmid36592877>{{cite journal |authors=Tjota MY, Sharma A, Wanjari P, Fitzpatrick C, Segal J, Antic T |title=TSC/MTOR mutated renal cell carcinoma with leiomyomatous stroma is a distinct entity: a comprehensive study of 12 cases |journal=Hum Pathol |volume=134 |issue= |pages=124–133 |date=April 2023 |pmid=36592877 |doi=10.1016/j.humpath.2022.12.015 |url=}}</ref> | ||
*Fibromyomatous stroma - '''key feature'''. | *Fibromyomatous stroma (smooth muscle stroma) - '''key feature'''. | ||
*Varied architecture: nested, solid, tubular, tubulopapillary. | |||
*WHO/ISUP grade 3 or 4. | |||
*Nuclei ''not'' polarized in the cell. | |||
DDx: | DDx: | ||
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==IHC== | ==IHC== | ||
Features:<ref name=pmid36592877/> | |||
*CD10 +ve. | |||
*CK7 +ve (most). | |||
*CA9 +ve. | |||
===Comparison between some renal tumours with clear cells=== | ===Comparison between some renal tumours with clear cells=== | ||
{| class="wikitable sortable" | {| class="wikitable sortable" | ||