Difference between revisions of "Radical cystectomy grossing"

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In men, the [[urinary bladder]] is usually removed along with the [[prostate gland]] (see [[cystoprostatectomy]]).
In men, the [[urinary bladder]] is usually removed along with the [[prostate gland]] (see [[cystoprostatectomy]]).


The ureters in these specimens often are assessed [[frozen section|intraoperatively]]. The occurance of [[urothelial carcinoma in situ|CIS]] is strongly associated with CIS in the [[urinary bladder]].<ref name=pmid25374918>{{Cite journal  | last1 = Zhou | first1 = H. | last2 = Ro | first2 = JY. | last3 = Truong | first3 = LD. | last4 = Ayala | first4 = AG. | last5 = Shen | first5 = SS. | title = Intraoperative frozen section evaluation of ureteral and urethral margins: studies of 203 consecutive radical cystoprostatectomy for men with bladder urothelial carcinoma. | journal = Am J Clin Exp Urol | volume = 2 | issue = 2 | pages = 156-60 | month =  | year = 2014 | doi =  | PMID = 25374918 }}</ref>
The [[ureter]]s in these cases are often are assessed [[frozen section|intraoperatively]]. The occurrence of [[urothelial carcinoma in situ|CIS]] is strongly associated with CIS in the [[urinary bladder]].<ref name=pmid25374918>{{Cite journal  | last1 = Zhou | first1 = H. | last2 = Ro | first2 = JY. | last3 = Truong | first3 = LD. | last4 = Ayala | first4 = AG. | last5 = Shen | first5 = SS. | title = Intraoperative frozen section evaluation of ureteral and urethral margins: studies of 203 consecutive radical cystoprostatectomy for men with bladder urothelial carcinoma. | journal = Am J Clin Exp Urol | volume = 2 | issue = 2 | pages = 156-60 | month =  | year = 2014 | doi =  | PMID = 25374918 }}</ref>
 
==Specimen opening==
*Orientation:
**Posterior - typically has serosa (shiny).
**Uterus, uterine tubes and ovaries posterior to bladder.
*[[Inking]]:
**Urethra margin - green ink.
**Anterior urinary bladder site of opening (blue ink):
***Line 1: anterior bladder base toward upper left.
***Line 2: anterior bladder base toward upper right.
**If total hysterectomy - soft tissue margin - black ink.
*Opening:
**Open anteriorly through the urethra and follow the ink upward to left and upward to right - such that anterior bladder wall can be flipped upward.
**Open the uterus - if present - with scissors through the external os with cuts on the lateral walls.
*Specimen should be pinned open on a large block of paraffin wax.
**A paper towel should be placed behind the specimen - between the specimen and paraffin wax.
*Place specimen(s) in [[formalin]].


==Protocol==
==Protocol==
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*Appearance: [tan/brown / white], [firm / friable].
*Appearance: [tan/brown / white], [firm / friable].
*Extension into perivescicular adipose tissue: [not identified, present].
*Extension into perivescicular adipose tissue: [not identified, present].
Other:
*[None / granular areas / hemorraghic areas / polypoid areas / polyps].


Representative sections:  
Representative sections:  
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*Section with deepest invasion.  
*Section with deepest invasion.  
*One section if fat invasion obvious, three sections if it is suspicious.  
*One section if fat invasion obvious, three sections if it is suspicious.  
*Suspicious granular areas.  
*Suspicious granular areas and polyps.  
*Left bladder wall at site of ureteric oriface.  
*Left bladder wall at site of ureteric oriface.  
*Right bladder wall at site of ureteric oriface.
*Right bladder wall at site of ureteric oriface.
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