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Difference between revisions of "Pulmonary pathology"
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===Lung histology=== | ===Lung histology=== | ||
==== | ====Bronchial mucosa==== | ||
*Ciliated pseudostratified epithelium. | |||
*Minimal/mild inflammation. | |||
*Small amount of smooth muscle. | |||
Metaplastic changes: | |||
*Goblet cells - described in association [[asthma]] and [[COPD]].<ref>{{cite journal |authors=Rogers DF |title=The airway goblet cell |journal=Int J Biochem Cell Biol |volume=35 |issue=1 |pages=1–6 |date=January 2003 |pmid=12467641 |doi=10.1016/s1357-2725(02)00083-3 |url=}}</ref> | |||
*Squamous - may precede dysplasia and malignancy. | |||
====Lung parenchyma==== | |||
Common: | Common: | ||
*Type I pneumocyte - cover most of the alveolar surface. | *Type I pneumocyte - cover most of the alveolar surface. | ||
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<pre> | <pre> | ||
Submitted as "Lung Mass" (Left Lower Lobe), Core Biopsy: | Submitted as "Lung Mass" (Left Lower Lobe), Core Biopsy: | ||
- | - Tiny cluster of indeterminate cells insufficient for a diagnosis, see comment. | ||
- Benign lung parenchyma. | - Benign lung parenchyma. | ||
- NEGATIVE for definite lesion. | - NEGATIVE for definite lesion. | ||
Comment: | Comment: | ||
Deepers were cut (x3). The radiologic findings are noted. A re-biopsy is | Deepers were cut (x3). The radiologic findings are noted. A re-biopsy is recommended. | ||
</pre> | </pre> | ||
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===Extralobar sequestration=== | ===Extralobar sequestration=== | ||
General: | General: | ||
*Typically not connected to airway tree/trachea. | *Typically not connected to airway tree/[[trachea]]. | ||
*Blood supply arises from aorta, ''not'' the pulmonary artery. | *Blood supply arises from aorta, ''not'' the pulmonary artery. | ||
*Mass lesion. | *Mass lesion. | ||