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Difference between revisions of "Pulmonary meningothelial-like nodule"
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Pulmonary meningothelial-like nodule (view source)
Revision as of 19:27, 6 October 2015
, 19:27, 6 October 2015+infobox
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = pulmonary chemodectoma | |||
| Micro = small cell nests (expanding alveolar septa) with whorled appearance/streaming; composed of bland cells with round/ovoid nuclei without appreciable nucleoli | |||
| Subtypes = | |||
| LMDDx = [[lung tumourlet]], poorly differentiated carcinoma, [[lobular breast carcinoma]] | |||
| Stains = | |||
| IHC = PR +ve, vimentin +ve, EMA +ve, CD56 +ve, chromogranin A -ve, synaptophysin -ve, S-100 -ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = tan or yellow nodules - pleural or parenchymal, typically 1-3 mm | |||
| Grossing = | |||
| Site = [[lung]] | |||
| Assdx = poorly understood association with [[lung tumours]] - esp. [[lung adenocarcinoma]] | |||
| Syndromes = | |||
| Clinicalhx = typically an incidential finding | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = none | |||
}} | |||
'''Pulmonary meningothelial-like nodule''', abbreviated '''MLN''', is a common benign finding in the [[lung]]. | '''Pulmonary meningothelial-like nodule''', abbreviated '''MLN''', is a common benign finding in the [[lung]]. | ||
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*May be grouped with ''pulmonary meningioma'' in the larger category ''primary pleuropulmonary meningothelial proliferations''.<ref name=pmid26291511>{{Cite journal | last1 = Weissferdt | first1 = A. | last2 = Tang | first2 = X. | last3 = Suster | first3 = S. | last4 = Wistuba | first4 = II. | last5 = Moran | first5 = CA. | title = Pleuropulmonary Meningothelial Proliferations: Evidence for a Common Histogenesis. | journal = Am J Surg Pathol | volume = | issue = | pages = | month = Aug | year = 2015 | doi = 10.1097/PAS.0000000000000489 | PMID = 26291511 }}</ref> | *May be grouped with ''pulmonary meningioma'' in the larger category ''primary pleuropulmonary meningothelial proliferations''.<ref name=pmid26291511>{{Cite journal | last1 = Weissferdt | first1 = A. | last2 = Tang | first2 = X. | last3 = Suster | first3 = S. | last4 = Wistuba | first4 = II. | last5 = Moran | first5 = CA. | title = Pleuropulmonary Meningothelial Proliferations: Evidence for a Common Histogenesis. | journal = Am J Surg Pathol | volume = | issue = | pages = | month = Aug | year = 2015 | doi = 10.1097/PAS.0000000000000489 | PMID = 26291511 }}</ref> | ||
*Can mimic [[metastasis|metastatic deposits]].<ref name=pmid24023559/><ref name=pmid23109985>{{Cite journal | last1 = Kfoury | first1 = H. | last2 = Arafah | first2 = MA. | last3 = Arafah | first3 = MM. | last4 = Alnassar | first4 = S. | last5 = Hajjar | first5 = W. | title = Mimicry of Minute Pulmonary Meningothelial-like Nodules to Metastatic Deposits in a Patient with Infiltrating Lobular Carcinoma: A Case Report and Review of the Literature. | journal = Korean J Pathol | volume = 46 | issue = 1 | pages = 87-91 | month = Feb | year = 2012 | doi = 10.4132/KoreanJPathol.2012.46.1.87 | PMID = 23109985 }}</ref> | *Can mimic [[metastasis|metastatic deposits]].<ref name=pmid24023559/><ref name=pmid23109985>{{Cite journal | last1 = Kfoury | first1 = H. | last2 = Arafah | first2 = MA. | last3 = Arafah | first3 = MM. | last4 = Alnassar | first4 = S. | last5 = Hajjar | first5 = W. | title = Mimicry of Minute Pulmonary Meningothelial-like Nodules to Metastatic Deposits in a Patient with Infiltrating Lobular Carcinoma: A Case Report and Review of the Literature. | journal = Korean J Pathol | volume = 46 | issue = 1 | pages = 87-91 | month = Feb | year = 2012 | doi = 10.4132/KoreanJPathol.2012.46.1.87 | PMID = 23109985 }}</ref> | ||
Associations: | Associations: | ||