Pulmonary lymphangitic carcinomatosis

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Pulmonary lymphangitic carcinomatosis, abbreviated PLC, is the presence of multiple foci of (metastatic) carcinoma in the lymphatic channels of the lung.[1]

General

  • Uncommon.[2]
  • Typically fatal.[3]
  • Dyspnea (shortness of breath).[4]

Radiology

  • Interstitial thickening.

DDx:

Microscopic

Features:

  • Carcinoma in multiple the lymphatic channels.

DDx:

Images

See also

References

  1. Gilchrist FJ, Alton H, Brundler MA, Edwards L, Plunkett A, Rao S (September 2011). "Pulmonary lymphangitic carcinomatosis presenting as severe interstitial lung disease in a 15-year-old female". Eur Respir Rev 20 (121): 208–10. doi:10.1183/09059180.00000911. PMID 21881149.
  2. Wallach JB, McGarry T, Torres J (January 2011). "Lymphangitic metastasis of recurrent renal cell carcinoma to the contralateral lung causing lymphangitic carcinomatosis and respiratory symptoms". Curr Oncol 18 (1): e35–7. PMC 3031363. PMID 21331270. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031363/.
  3. Tighe D, Cavilla S, Simcock R (July 2014). "Pulmonary lymphangitic carcinomatosis from head and neck squamous cell carcinoma". Int J Oral Maxillofac Surg 43 (7): 806–10. doi:10.1016/j.ijom.2013.12.003. PMID 24612960.
  4. 4.0 4.1 Gilchrist FJ, Alton H, Brundler MA, Edwards L, Plunkett A, Rao S (September 2011). "Pulmonary lymphangitic carcinomatosis presenting as severe interstitial lung disease in a 15-year-old female". Eur Respir Rev 20 (121): 208–10. doi:10.1183/09059180.00000911. PMID 21881149.
  5. Kanthan R, Senger JL, Diudea D (2010). "Pulmonary lymphangitic carcinomatosis from squamous cell carcinoma of the cervix". World J Surg Oncol 8: 107. doi:10.1186/1477-7819-8-107. PMC 3006383. PMID 21129213. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006383/.