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Difference between revisions of "Pulmonary hypertension"
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Pulmonary hypertension (view source)
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'''Pulmonary | [[Image:Angiomatoid (plexiform) and dilatation lesions (4348913976).jpg|thumb|right|300px|Plexiform lesion of the lung, a finding of pulmonary hypertension. (WC/Rosen)]] | ||
'''Pulmonary hypertension''' is bad stuff that arises from [[heart]] problems, an assortment of lung pathologies and some drugs. | |||
''Hypertension'', more generally, is dealt with in the ''[[hypertension]]'' article. | |||
==General classification== | ==General classification== | ||
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===Microscopic=== | ===Microscopic=== | ||
*Like chronic pulmonary hypertension due to congenital heart disease but ''without'' the congenital heart disease.<ref name=dccpad/> | *Like chronic pulmonary hypertension due to [[congenital heart disease]] but ''without'' the congenital heart disease.<ref name=dccpad/> | ||
**Classified by ''Heath-Edwards classification'' (see below) into six grades. | **Classified by ''Heath-Edwards classification'' (see below) into six grades. | ||
====Images==== | |||
<gallery> | |||
Image:Angiomatoid_(plexiform)_and_dilatation_lesions_(4348914566).jpg | Plexiform lesion of the lung. (WC/Rosen) | |||
Image:Angiomatoid_(plexiform)_and_dilatation_lesions_(4348913976).jpg | Plexiform lesion of the lung. (WC/Rosen) | |||
Image:Angiomatoid (plexiform) and dilatation lesions (4348915198).jpg| Plexiform lesion of the lung. (WC/Rosen) | |||
</gallery> | |||
==Pulmonary veno-occlusive disease== | ==Pulmonary veno-occlusive disease== | ||
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===General=== | ===General=== | ||
Clinical:<ref name=PPP393-6>{{Ref PPP|393-6}}</ref> | Clinical:<ref name=PPP393-6>{{Ref PPP|393-6}}</ref> | ||
*Gradual dyspnea | *Gradual [[dyspnea]]. | ||
*+/-Non-productive cough. | *+/-Non-productive cough. | ||
*+/- Clubbing. | *+/- Clubbing. | ||
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**Grade 4: | **Grade 4: | ||
***Intima: '''"plexiform lesions"''' + fibrous & fibroelastic reaction, + cellular intimal reaction. | ***Intima: '''"plexiform lesions"''' + fibrous & fibroelastic reaction, + cellular intimal reaction. | ||
*****Plexiform lesions = multiple channels that are dilated, | *****Plexiform lesions = multiple channels that are dilated, associated with loss of elastic laminae; thought to arise at branch points due to aberrant WSS.<ref>[http://pathhsw5m54.ucsf.edu/overview/vessels.html http://pathhsw5m54.ucsf.edu/overview/vessels.html]</ref> | ||
***Media: generalized dilation +/- '''local "dilation lesions"'''. | ***Media: generalized dilation +/- '''local "dilation lesions"'''. | ||
***Micrographs: [http://pathhsw5m54.ucsf.edu/overview/vessels.html Plexiform lesions (ucsf.edu)], [http://www.pvrireview.org/viewimage.asp?img=PVRIReview_2009_1_1_34_44882_u6.jpg Plexiform lesions (pvrireview.org)]. | ***Micrographs: [http://pathhsw5m54.ucsf.edu/overview/vessels.html Plexiform lesions (ucsf.edu)], [http://www.pvrireview.org/viewimage.asp?img=PVRIReview_2009_1_1_34_44882_u6.jpg Plexiform lesions (pvrireview.org)]. | ||