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Difference between revisions of "Pulmonary cytopathology"
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There is a proposed standard for EBUS specimens:<ref name=pmid22246929>{{Cite journal | last1 = Nayak | first1 = A. | last2 = Sugrue | first2 = C. | last3 = Koenig | first3 = S. | last4 = Wasserman | first4 = PG. | last5 = Hoda | first5 = S. | last6 = Morgenstern | first6 = NJ. | title = Endobronchial ultrasound-guided transbronchial needle aspirate (EBUS-TBNA): a proposal for on-site adequacy criteria. | journal = Diagn Cytopathol | volume = 40 | issue = 2 | pages = 128-37 | month = Feb | year = 2012 | doi = 10.1002/dc.21517 | PMID = 22246929 }}</ref> | There is a proposed standard for EBUS specimens:<ref name=pmid22246929>{{Cite journal | last1 = Nayak | first1 = A. | last2 = Sugrue | first2 = C. | last3 = Koenig | first3 = S. | last4 = Wasserman | first4 = PG. | last5 = Hoda | first5 = S. | last6 = Morgenstern | first6 = NJ. | title = Endobronchial ultrasound-guided transbronchial needle aspirate (EBUS-TBNA): a proposal for on-site adequacy criteria. | journal = Diagn Cytopathol | volume = 40 | issue = 2 | pages = 128-37 | month = Feb | year = 2012 | doi = 10.1002/dc.21517 | PMID = 22246929 }}</ref> | ||
*> 5 low power fields (×10 objective) with >= 100 lymphocytes and < 2 groups of bronchial cells. | *> 5 low power fields (×10 objective) with >= 100 lymphocytes and < 2 groups of bronchial cells. | ||
Note: | |||
*A simplified version: 5 fields of view x 100 cells/1 field of view = 500 cells. | |||
===Other specimens=== | ===Other specimens=== | ||
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Features: | Features: | ||
*Casts of frothy material/large proteinaceous debris - approximately the size of an alveolus. | *Casts of frothy material/large proteinaceous debris - approximately the size of an alveolus. | ||
DDx: | |||
*[[Pulmonary alveolar proteinosis]]. | |||
==Aspergillosis== | ==Aspergillosis== | ||
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| '''Present''' | | '''Present''' | ||
| Present r/i squamous (strong) | | Present r/i squamous (strong) | ||
|- | |||
| Image | |||
| [[Image:Lung small cell carcinoma -- extremely high mag.jpg|thumb|center|120px|SmCC - Pap stain. (WC)]] | |||
| [[Image:Lung adenocarcinoma - Pap stain -- very high mag.jpg|thumb|center|120px|LA - Pap stain. (WC)]] | |||
| [[Image:Squamous carcinoma - lung FNA -- very high mag.jpg|thumb|center|120px|SCC - Pap stain. (WC)]] | |||
| <!-- Value --> | |||
|} | |} | ||
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Image: Lung adenocarcinoma - Pap stain - alt -- very high mag.jpg | LA - Pap - very high mag. (WC) | Image: Lung adenocarcinoma - Pap stain - alt -- very high mag.jpg | LA - Pap - very high mag. (WC) | ||
Image: Lung adenocarcinoma - Diff-Quik -- high mag.jpg | LA - DQ - high mag. (WC) | Image: Lung adenocarcinoma - Diff-Quik -- high mag.jpg | LA - [[Diff-Quik stain|DQ]] - high mag. (WC) | ||
Image: Lung adenocarcinoma - Diff-Quik -- very high mag.jpg | LA - DQ - very high mag. (WC) | Image: Lung adenocarcinoma - Diff-Quik -- very high mag.jpg | LA - DQ - very high mag. (WC) | ||
</gallery> | </gallery> | ||
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====Image==== | ====Image==== | ||
=====Case 1===== | |||
<gallery> | |||
Image:Small_cell_lung_cancer_-_cytology.jpg | SmCC showing nuclear moulding - [[Field stain]]. (WC) | |||
</gallery> | |||
=====Case 2===== | |||
<gallery> | <gallery> | ||
Image: | Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg | SmCC - [[Diff-Quik]] - high mag. (WC) | ||
Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg | SmCC - Diff-Quik - very high mag. (WC) | |||
Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg | SmCC - Diff-Quik - extremely high mag. (WC) | |||
Image: Lung small cell carcinoma -- very high mag.jpg | SmCC - [[Pap stain]] - very high mag. (WC) | |||
Image: Lung small cell carcinoma -- extremely high mag.jpg | SmCC - Pap stain - extremely high mag. (WC) | |||
</gallery> | |||
=====Case 3===== | |||
<gallery> | |||
Image: Small cell carcinoma - BRB -- high mag.jpg | SmCC - high mag. | |||
Image: Small cell carcinoma - BRB - alt -- high mag.jpg | SmCC - high mag. | |||
Image: Small cell carcinoma - BRB - alt 2 -- high mag.jpg | SmCC - high mag. | |||
Image: Small cell carcinoma - BRB -- very high mag.jpg | SmCC - very high mag. | |||
Image: Small cell carcinoma - BRB - alt -- very high mag.jpg | SmCC - very high mag. | |||
Image: Small cell carcinoma - BRB - alt 2 -- very high mag.jpg | SmCC - very high mag. | |||
Image: Small cell carcinoma - BRB -- very high mag.gif | SmCC - high very mag. | |||
</gallery> | </gallery> | ||