Pulmonary carcinoid tumourlet

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Pulmonary carcinoid tumourlet, also carcinoid tumourlet, is a small benign proliferation of Kulchitsky cells. It can be understood as a smaller version of the typical lung carcinoid tumour.

General

  • Neuroendocrine cell proliferation.[1]
  • Arise from Kulchitsky cells of the bronchial epithelium.[2]

Microscopic

Features:

  • Nests of cells - classic pattern.
    • Salt and pepper chromatin - key feature.
  • Size criterion: <5 mm.[3][4]

DDx:

Images

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A. Lymph Node, Station 4R, Lymphadenectomy:
- Lymph node, NEGATIVE for malignancy.

B. Lymph Node, Station 11R, Lymphadenectomy:
- Lymph node, NEGATIVE for malignancy.

C. Lung, Right Middle Lobe, Lobectomy:
- Typical carcinoid tumour (13 mm maximal dimension).
- Carcinoid tumourlet (3 mm maximal dimension).
- Margins clear of tumour.
- Please see tumour summary.

See also

References

  1. Bennett, GL.; Chew, FS. (Mar 1994). "Pulmonary carcinoid tumorlets.". AJR Am J Roentgenol 162 (3): 568. PMID 8109497.
  2. Ramón Capilla, M.; Arnau Obrer, A.; Navarro Ibáñez, R.; Galbis Caravajal, J.; Traves Zapata, V.; Cantó Armengod, A. (Nov 1996). "[Pulmonary tumorlet. Report of 5 cases].". Arch Bronconeumol 32 (9): 489-91. PMID 9064089.
  3. URL: http://pathhsw5m54.ucsf.edu/case7/image75.html. Accessed on: 23 January 2012.
  4. He, P.; Gu, X.; Wu, Q.; Lin, Y.; Gu, Y.; He, J. (Dec 2012). "Pulmonary carcinoid tumorlet without underlying lung disease: analysis of its relationship to fibrosis.". J Thorac Dis 4 (6): 655-8. doi:10.3978/j.issn.2072-1439.2012.06.11. PMID 23205296.