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Difference between revisions of "Pulmonary blastoma"
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'''Pulmonary blastoma''' is a very rare tumour of the [[lung]]. These tumours are often lumped into the ''pulmonary sarcomatoid carcinomas'' group.<ref name=pmid19124452>{{Cite journal | last1 = Pelosi | first1 = G. | last2 = Sonzogni | first2 = A. | last3 = De Pas | first3 = T. | last4 = Galetta | first4 = D. | last5 = Veronesi | first5 = G. | last6 = Spaggiari | first6 = L. | last7 = Manzotti | first7 = M. | last8 = Fumagalli | first8 = C. | last9 = Bresaola | first9 = E. | title = Review article: pulmonary sarcomatoid carcinomas: a practical overview. | journal = Int J Surg Pathol | volume = 18 | issue = 2 | pages = 103-20 | month = Apr | year = 2010 | doi = 10.1177/1066896908330049 | PMID = 19124452 }}</ref> | '''Pulmonary blastoma''' is a very rare tumour of the [[lung]]. These tumours are often lumped into the ''[[pulmonary sarcomatoid carcinomas]]'' group.<ref name=pmid19124452>{{Cite journal | last1 = Pelosi | first1 = G. | last2 = Sonzogni | first2 = A. | last3 = De Pas | first3 = T. | last4 = Galetta | first4 = D. | last5 = Veronesi | first5 = G. | last6 = Spaggiari | first6 = L. | last7 = Manzotti | first7 = M. | last8 = Fumagalli | first8 = C. | last9 = Bresaola | first9 = E. | title = Review article: pulmonary sarcomatoid carcinomas: a practical overview. | journal = Int J Surg Pathol | volume = 18 | issue = 2 | pages = 103-20 | month = Apr | year = 2010 | doi = 10.1177/1066896908330049 | PMID = 19124452 }}</ref> | ||
The article deals with ''well-differentiated fetal adenocarcinoma'' and ''classic biphasic pulmonary blastoma''. | |||
[[Pleuropulmonary blastoma]] is dealt with in a separate article. | |||
==General== | ==General== | ||
*Very rare ~ 100 cases in the literature.<ref name=pmid23049565 >{{Cite journal | last1 = Alahwal | first1 = MS. | last2 = Maniyar | first2 = IH. | last3 = Saleem | first3 = F. | last4 = Alshiekh | first4 = M. | title = Pulmonary blastoma: a rare primary lung malignancy. | journal = Case Rep Med | volume = 2012 | issue = | pages = 471613 | month = | year = 2012 | doi = 10.1155/2012/471613 | PMID = 23049565 | PMC = 3461274 }}</ref> | *Very rare ~ 100 cases in the literature.<ref name=pmid23049565 >{{Cite journal | last1 = Alahwal | first1 = MS. | last2 = Maniyar | first2 = IH. | last3 = Saleem | first3 = F. | last4 = Alshiekh | first4 = M. | title = Pulmonary blastoma: a rare primary lung malignancy. | journal = Case Rep Med | volume = 2012 | issue = | pages = 471613 | month = | year = 2012 | doi = 10.1155/2012/471613 | PMID = 23049565 | PMC = 3461274 }}</ref> | ||
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*Well-differentiated fetal adenocarcinoma (WDFA). | *Well-differentiated fetal adenocarcinoma (WDFA). | ||
*Classic biphasic pulmonary blastoma (CBPB). | *Classic biphasic pulmonary blastoma (CBPB). | ||
*Pleuropulmonary blastoma. | *[[Pleuropulmonary blastoma]]. | ||
**Now considered a separate entity.<ref name=pmid21513998>{{Cite journal | last1 = Van Loo | first1 = S. | last2 = Boeykens | first2 = E. | last3 = Stappaerts | first3 = I. | last4 = Rutsaert | first4 = R. | title = Classic biphasic pulmonary blastoma: a case report and review of the literature. | journal = Lung Cancer | volume = 73 | issue = 2 | pages = 127-32 | month = Aug | year = 2011 | doi = 10.1016/j.lungcan.2011.03.018 | PMID = 21513998 }}</ref> | **Now considered a separate entity.<ref name=pmid21513998>{{Cite journal | last1 = Van Loo | first1 = S. | last2 = Boeykens | first2 = E. | last3 = Stappaerts | first3 = I. | last4 = Rutsaert | first4 = R. | title = Classic biphasic pulmonary blastoma: a case report and review of the literature. | journal = Lung Cancer | volume = 73 | issue = 2 | pages = 127-32 | month = Aug | year = 2011 | doi = 10.1016/j.lungcan.2011.03.018 | PMID = 21513998 }}</ref> | ||
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*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?s=20080802170406269 Pulmonary blastoma (surgicalpathologyatlas.com)]. | *[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?s=20080802170406269 Pulmonary blastoma (surgicalpathologyatlas.com)]. | ||
*[http://www.flickr.com/photos/pulmonary_pathology/5463058190/ Pulmonary blastoma (flickr.com/Yale Rosen)]. | *[http://www.flickr.com/photos/pulmonary_pathology/5463058190/ Pulmonary blastoma (flickr.com/Yale Rosen)]. | ||
==IHC== | ==IHC== | ||
Features:<ref>{{Cite journal | last1 = Zhang | first1 = GQ. | last2 = Fang | first2 = XZ. | last3 = Wang | first3 = BQ. | last4 = Sun | first4 = W. | last5 = Salai | first5 = AD. | title = [Clinicopathological and immunohistochemical features of pulmonary blastoma: analysis of 4 cases and review of the literature]. | journal = Zhonghua Yi Xue Za Zhi | volume = 87 | issue = 15 | pages = 1040-2 | month = Apr | year = 2007 | doi = | PMID = 17672968 }}</ref> | Features:<ref>{{Cite journal | last1 = Zhang | first1 = GQ. | last2 = Fang | first2 = XZ. | last3 = Wang | first3 = BQ. | last4 = Sun | first4 = W. | last5 = Salai | first5 = AD. | title = [Clinicopathological and immunohistochemical features of pulmonary blastoma: analysis of 4 cases and review of the literature]. | journal = Zhonghua Yi Xue Za Zhi | volume = 87 | issue = 15 | pages = 1040-2 | month = Apr | year = 2007 | doi = | PMID = 17672968 }}</ref> | ||
*TTF-1 +ve. | *[[TTF-1]] +ve. | ||
*S-100 -ve. | *S-100 -ve. | ||
*Vimentin -ve.{{fact}} | *Vimentin -ve.{{fact}} | ||
*EMA -ve. | *[[EMA]] -ve. | ||
==See also== | ==See also== | ||