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Difference between revisions of "Prostate gland"
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Notes: | Notes: | ||
*Tufted epithelium is a strong indicator of benignancy; however two uncommon prostate cancer typically have tufted epithelium: | *Tufted epithelium is a strong indicator of benignancy; however two uncommon prostate cancer variants typically have tufted epithelium: | ||
**[[Pseudohyperplastic adenocarcinoma]]. | **[[Pseudohyperplastic adenocarcinoma]]. | ||
**[[Foamy gland carcinoma]]. | **[[Foamy gland carcinoma]]. | ||
| Line 49: | Line 49: | ||
Normal prostate: | Normal prostate: | ||
*[[AMACR]] -ve (mark epithelial cells). | *[[AMACR]] -ve (mark epithelial cells). | ||
*CK5/6 +ve,<ref name=pmid19605815>{{Cite journal | last1 = Trpkov | first1 = K. | last2 = Bartczak-McKay | first2 = J. | last3 = Yilmaz | first3 = A. | title = Usefulness of cytokeratin 5/6 and AMACR applied as double sequential immunostains for diagnostic assessment of problematic prostate specimens. | journal = Am J Clin Pathol | volume = 132 | issue = 2 | pages = 211-20; quiz 307 | month = Aug | year = 2009 | doi = 10.1309/AJCPGFJP83IXZEUR | PMID = 19605815 }}</ref> p63 +ve, HMWCK +ve (mark basal cells). | *[[CK5/6]] +ve,<ref name=pmid19605815>{{Cite journal | last1 = Trpkov | first1 = K. | last2 = Bartczak-McKay | first2 = J. | last3 = Yilmaz | first3 = A. | title = Usefulness of cytokeratin 5/6 and AMACR applied as double sequential immunostains for diagnostic assessment of problematic prostate specimens. | journal = Am J Clin Pathol | volume = 132 | issue = 2 | pages = 211-20; quiz 307 | month = Aug | year = 2009 | doi = 10.1309/AJCPGFJP83IXZEUR | PMID = 19605815 }}</ref> p63 +ve, HMWCK +ve (mark basal cells). | ||
*PSA (prostate-specific antigen) +ve, PSAP (prostatic-specific acid phosphatase) +ve. | *PSA ([[prostate-specific antigen]]) +ve, PSAP ([[prostatic-specific acid phosphatase]]) +ve. | ||
==Sign out== | ==Sign out== | ||