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Difference between revisions of "Prostate chips grossing"
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This article deals with '''prostate chips grossing'''. ''TURP specimens'' | This article deals with '''prostate chips grossing'''. ''TURP specimens'' and ''TURP grossing'' redirect here. | ||
==Introduction== | ==Introduction== | ||
Prostate chips are generated from ''transurethral resection of the prostate'' (TURP) procedures. These are generally for relieving urinary obstruction due to [[nodular hyperplasia of the prostate]] (benign prostatic hyperplasia); however, urinary obstruction may be secondary to [[prostate cancer]]. Thus, the job of the pathologist here, usually, is excluding an incidental [[cancer]]. | Prostate chips are generated from ''transurethral resection of the prostate'' (TURP) procedures. These are generally for relieving urinary obstruction due to [[nodular hyperplasia of the prostate]] (benign prostatic hyperplasia); however, urinary obstruction may be secondary to [[prostate cancer]]. Thus, the job of the pathologist here, usually, is excluding an incidental [[cancer]]. | ||
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***16 grams: 6-8 cassettes for 12 grams + 1 cassette = 7-9 cassettes. | ***16 grams: 6-8 cassettes for 12 grams + 1 cassette = 7-9 cassettes. | ||
***21 grams: 6-8 cassettes for 12 grams + 2 cassettes = 7-9 cassettes. | ***21 grams: 6-8 cassettes for 12 grams + 2 cassettes = 7-9 cassettes. | ||
Note: | |||
*If a minimal cancer is found in a partially submitted specimen, it is reasonable to stop there as submitting more tissue or the remainder is unlikely to change the [[prostate cancer grading|grade]] or extent of involvement.<ref name=pmid18684032>{{Cite journal | last1 = Trpkov | first1 = K. | last2 = Thompson | first2 = J. | last3 = Kulaga | first3 = A. | last4 = Yilmaz | first4 = A. | title = How much tissue sampling is required when unsuspected minimal prostate carcinoma is identified on transurethral resection? | journal = Arch Pathol Lab Med | volume = 132 | issue = 8 | pages = 1313-6 | month = Aug | year = 2008 | doi = 10.1043/1543-2165(2008)132[1313:HMTSIR]2.0.CO;2 | PMID = 18684032 }}</ref> | |||
=====Formula===== | =====Formula===== | ||
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<br>Where: | <br>Where: | ||
<br>N = number of blocks. | <br>N = number of blocks. | ||
<br>m = mass of the prostate tissue. | <br>m = mass of the prostate tissue in grams. | ||
===Alternate approaches=== | ===Alternate approaches=== | ||