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Difference between revisions of "Prostate cancer grading"
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→Tertiary Gleason pattern
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**Koloffa ''et al''<ref name=Koloffa/> notes that some define it as: the third most prevalent pattern and most require that it is a higher grade than the two dominant patterns. | **Koloffa ''et al''<ref name=Koloffa/> notes that some define it as: the third most prevalent pattern and most require that it is a higher grade than the two dominant patterns. | ||
***Parsed with the all the subtleties - a working definition could be: The third most prevalent pattern ''and'' a higher grade than the two dominant patterns ''or'' a pattern that is seen in less than 5% of the tumour and of higher grade than one pattern that comprises >95% of the tumour. | ***Parsed with the all the subtleties - a working definition could be: The third most prevalent pattern ''and'' a higher grade than the two dominant patterns ''or'' a pattern that is seen in less than 5% of the tumour and of higher grade than one pattern that comprises >95% of the tumour. | ||
Significance: | |||
*The presence of a tertiary patterns adversely affect the prognosis; however, the prognosis is not as bad as when the tertiary pattern is the secondary pattern, i.e. 3+4 tertiary 5 has a better prognosis than 3+5 (with some small amount of pattern 4).<ref name=Ref_GUP72>{{Ref GUP|72}}</ref> | |||
Use: | |||
*It is only used for prostatectomies. | |||
====Examples==== | ====Examples==== | ||