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Difference between revisions of "Prostate cancer"
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*Associated with a poor prognosis.<ref name=pmid19246509>{{Cite journal | last1 = Henry | first1 = PC. | last2 = Evans | first2 = AJ. | title = Intraductal carcinoma of the prostate: a distinct histopathological entity with important prognostic implications. | journal = J Clin Pathol | volume = 62 | issue = 7 | pages = 579-83 | month = Jul | year = 2009 | doi = 10.1136/jcp.2009.065003 | PMID = 19246509 }}</ref> | *Associated with a poor prognosis.<ref name=pmid19246509>{{Cite journal | last1 = Henry | first1 = PC. | last2 = Evans | first2 = AJ. | title = Intraductal carcinoma of the prostate: a distinct histopathological entity with important prognostic implications. | journal = J Clin Pathol | volume = 62 | issue = 7 | pages = 579-83 | month = Jul | year = 2009 | doi = 10.1136/jcp.2009.065003 | PMID = 19246509 }}</ref> | ||
*Strong association with aggressive invasive carcinomas on prostatectomy when identified in isolation on biopsy.<ref name=pmid20723921>{{Cite journal | last1 = Robinson | first1 = BD. | last2 = Epstein | first2 = JI. | title = Intraductal carcinoma of the prostate without invasive carcinoma on needle biopsy: emphasis on radical prostatectomy findings. | journal = J Urol | volume = 184 | issue = 4 | pages = 1328-33 | month = Oct | year = 2010 | doi = 10.1016/j.juro.2010.06.017 | PMID = 20723921 }}</ref> | *Strong association with aggressive invasive carcinomas on prostatectomy when identified in isolation on biopsy.<ref name=pmid20723921>{{Cite journal | last1 = Robinson | first1 = BD. | last2 = Epstein | first2 = JI. | title = Intraductal carcinoma of the prostate without invasive carcinoma on needle biopsy: emphasis on radical prostatectomy findings. | journal = J Urol | volume = 184 | issue = 4 | pages = 1328-33 | month = Oct | year = 2010 | doi = 10.1016/j.juro.2010.06.017 | PMID = 20723921 }}</ref> | ||
*High interobserver variability among experts ~43% agreement.<ref name=pmid25263387>{{Cite journal | last1 = Iczkowski | first1 = KA. | last2 = Egevad | first2 = L. | last3 = Ma | first3 = J. | last4 = Harding-Jackson | first4 = N. | last5 = Algaba | first5 = F. | last6 = Billis | first6 = A. | last7 = Camparo | first7 = P. | last8 = Cheng | first8 = L. | last9 = Clouston | first9 = D. | title = Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists. | journal = Ann Diagn Pathol | volume = 18 | issue = 6 | pages = 333-42 | month = Dec | year = 2014 | doi = 10.1016/j.anndiagpath.2014.08.010 | PMID = 25263387 }}</ref> | |||
**For comparison: HGPIN ~70% agreement, invasive carcinoma ~73% agreement. | |||
===Microscopic=== | ===Microscopic=== | ||