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Difference between revisions of "Postradiation prostatic carcinoma"
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Postradiation prostatic carcinoma (view source)
Revision as of 17:56, 24 July 2015
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| Symptoms = | | Symptoms = | ||
| Prevalence = uncommon | | Prevalence = uncommon | ||
| Bloodwork = elevated PSA or increasing PSA | | Bloodwork = elevated [[PSA]] or increasing PSA | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
| Line 30: | Line 30: | ||
| Tx = salvage prostatectomy | | Tx = salvage prostatectomy | ||
}} | }} | ||
'''Postradiation prostatic carcinoma''', also '''prostate carcinoma after radiation therapy''', is uncommon but may be challenging to diagnose.<ref name=pmid10524518>{{Cite journal | last1 = Cheng | first1 = L. | last2 = Cheville | first2 = JC. | last3 = Bostwick | first3 = DG. | title = Diagnosis of prostate cancer in needle biopsies after radiation therapy. | journal = Am J Surg Pathol | volume = 23 | issue = 10 | pages = 1173-83 | month = Oct | year = 1999 | doi = | PMID = 10524518 }}</ref> | '''Postradiation prostatic carcinoma''', also '''prostate carcinoma after radiation therapy''', is a type of [[postradiation prostate cancer]]. It is uncommon but may be challenging to diagnose.<ref name=pmid10524518>{{Cite journal | last1 = Cheng | first1 = L. | last2 = Cheville | first2 = JC. | last3 = Bostwick | first3 = DG. | title = Diagnosis of prostate cancer in needle biopsies after radiation therapy. | journal = Am J Surg Pathol | volume = 23 | issue = 10 | pages = 1173-83 | month = Oct | year = 1999 | doi = | PMID = 10524518 }}</ref> | ||
==General== | ==General== | ||
*Overcall and undercall are both seen.<ref name=pmid10524518/> | *Overcall and undercall are both seen.<ref name=pmid10524518/> | ||
*Commonly missed on core biopsies. | *Commonly missed on core biopsies.<ref name=pmid10524518/> | ||
*History of radiation. | *History of radiation. | ||
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===Images=== | ===Images=== | ||
====Case==== | |||
<gallery> | <gallery> | ||
Image: Prostatic carcinoma and radiation changes -- intermed mag.jpg | PC and RC - intermed. mag. | Image: Prostatic carcinoma and radiation changes -- intermed mag.jpg | PC and RC - intermed. mag. | ||
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Image: Radiation changes in the prostate - alt -- very high mag.jpg | RC - very high mag. | Image: Radiation changes in the prostate - alt -- very high mag.jpg | RC - very high mag. | ||
</gallery> | </gallery> | ||
====www==== | |||
*[http://webpathology.com/image.asp?case=97&n=6 Prostate cancer with radiation changes (webpathology.com)]. | |||
*[http://webpathology.com/image.asp?case=97&n=7 Prostate cancer with radiation changes (webpathology.com)]. | |||
==IHC== | ==IHC== | ||
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===Images=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image: Prostatic carcinoma and radiation changes - IHC -- low mag.jpg | PC and RC - low mag. | Image: Prostatic carcinoma and radiation changes - IHC -- low mag.jpg | PC and RC (AMACR-CK5/6) - low mag. | ||
Image: Prostatic carcinoma and radiation changes - IHC -- intermed mag.jpg | PC and RC - intermed. mag. | Image: Prostatic carcinoma and radiation changes - IHC -- intermed mag.jpg | PC and RC (AMACR-CK5/6) - intermed. mag. | ||
Image: Prostatic carcinoma and radiation changes - IHC -- high mag.jpg | PC and RC - high mag. | Image: Prostatic carcinoma and radiation changes - IHC -- high mag.jpg | PC and RC (AMACR-CK5/6) - high mag. | ||
</gallery> | </gallery> | ||