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Difference between revisions of "Post-transplant lymphoproliferative disorder"
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Post-transplant lymphoproliferative disorder (view source)
Revision as of 15:47, 3 March 2011
, 15:47, 3 March 2011→General
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*Rare. | *Rare. | ||
*B cell neoplasm associated with EBV.<ref>URL: [http://emedicine.medscape.com/article/431364-overview http://emedicine.medscape.com/article/431364-overview]. Accessed on: 10 February 2011.</ref><ref name=pmid15660500>{{cite journal |author=Gottschalk S, Rooney CM, Heslop HE |title=Post-transplant lymphoproliferative disorders |journal=Annu. Rev. Med. |volume=56 |issue= |pages=29–44 |year=2005 |pmid=15660500 |doi=10.1146/annurev.med.56.082103.104727 |url=}}</ref> | *B cell neoplasm associated with EBV.<ref>URL: [http://emedicine.medscape.com/article/431364-overview http://emedicine.medscape.com/article/431364-overview]. Accessed on: 10 February 2011.</ref><ref name=pmid15660500>{{cite journal |author=Gottschalk S, Rooney CM, Heslop HE |title=Post-transplant lymphoproliferative disorders |journal=Annu. Rev. Med. |volume=56 |issue= |pages=29–44 |year=2005 |pmid=15660500 |doi=10.1146/annurev.med.56.082103.104727 |url=}}</ref> | ||
**Develop from a latent EBV infection - which may be detectable by the presence of "passenger cells" = scattered EBER positive lymphocytes.<ref>URL: [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422031/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422031/]. Accessed on: 3 March 2011.</ref> | |||
*Commonly in the GI tract as it gets the most immunosuppression; immunosuppressives are taken orally -- not cleaned by the [[liver]] prior to reaching the GI tract. | *Commonly in the GI tract as it gets the most immunosuppression; immunosuppressives are taken orally -- not cleaned by the [[liver]] prior to reaching the GI tract. | ||