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Difference between revisions of "Polymorphous adenocarcinoma"
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Polymorphous adenocarcinoma (view source)
Revision as of 16:59, 23 November 2013
, 16:59, 23 November 2013more
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| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = | | Prevalence = uncommon (varies by study) | ||
| Bloodwork = | | Bloodwork = | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
| Prognosis = | | Prognosis = good | ||
| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = | ||
| Line 31: | Line 31: | ||
==General== | ==General== | ||
*Female:male ~= 2:1. | *Female:male ~= 2:1. | ||
*Older people ~50-70 years old. | *Older people ~50-70 years old. | ||
*Large variably in the prevalence reported - suggests a lacking of reproducibility in the [[diagnosis]].<ref name=pmid23320410/> | |||
*Slow growing - metastases rare - prognosis good.<ref name=pmid18327037>{{Cite journal | last1 = Paleri | first1 = V. | last2 = Robinson | first2 = M. | last3 = Bradley | first3 = P. | title = Polymorphous low-grade adenocarcinoma of the head and neck. | journal = Curr Opin Otolaryngol Head Neck Surg | volume = 16 | issue = 2 | pages = 163-9 | month = Apr | year = 2008 | doi = 10.1097/MOO.0b013e3282f70441 | PMID = 18327037 }}</ref><ref name=pmid23618791>{{Cite journal | last1 = Fife | first1 = TA. | last2 = Smith | first2 = B. | last3 = Sullivan | first3 = CA. | last4 = Browne | first4 = JD. | last5 = Waltonen | first5 = JD. | title = Polymorphous low-grade adenocarcinoma: a 17 patient case series. | journal = Am J Otolaryngol | volume = 34 | issue = 5 | pages = 445-8 | month = | year = | doi = 10.1016/j.amjoto.2013.03.012 | PMID = 23618791 }}</ref> | |||
==Gross== | |||
*Tumour of the minor [[salivary gland]]s.<ref name=pmid24021444>{{Cite journal | last1 = Andreu-Barasoain | first1 = M. | last2 = Vicente-Martín | first2 = FJ. | last3 = Gómez de la Fuente | first3 = E. | last4 = Salamanca-Santamaría | first4 = J. | last5 = Pampín-Franco | first5 = A. | last6 = López-Estebaranz | first6 = JL. | title = Polymorphous low-grade adenocarcinoma in the upper lip: a well-described but infrequently recognized tumor. | journal = Dermatol Online J | volume = 19 | issue = 8 | pages = 19265 | month = | year = 2013 | doi = | PMID = 24021444 }}</ref> | |||
*Almost exclusively in the [[oral cavity]] - usually palate.<ref name=pmid18327037/> | |||
==Microscopic== | ==Microscopic== | ||
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**Cytoplasm: eosinophilic. | **Cytoplasm: eosinophilic. | ||
*Indistinct cell borders. | *Indistinct cell borders. | ||
Note: | |||
*'''Always'''' a low-grade tumour - by definition. | |||
DDx: | DDx: | ||