Difference between revisions of "Pleural invasion"

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'''Pleural invasion''' is the presence of tumour in the [[pleura]]. Pleural invasion is poor prognosticator in [[lung cancer]].<ref name=pmid19057261>{{Cite journal  | last1 = Travis | first1 = WD. | last2 = Brambilla | first2 = E. | last3 = Rami-Porta | first3 = R. | last4 = Vallières | first4 = E. | last5 = Tsuboi | first5 = M. | last6 = Rusch | first6 = V. | last7 = Goldstraw | first7 = P. | title = Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer. | journal = J Thorac Oncol | volume = 3 | issue = 12 | pages = 1384-90 | month = Dec | year = 2008 | doi = 10.1097/JTO.0b013e31818e0d9f | PMID = 19057261 }}</ref><ref name=pmid15999057>{{Cite journal  | last1 = Shimizu | first1 = K. | last2 = Yoshida | first2 = J. | last3 = Nagai | first3 = K. | last4 = Nishimura | first4 = M. | last5 = Ishii | first5 = G. | last6 = Morishita | first6 = Y. | last7 = Nishiwaki | first7 = Y. | title = Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer. | journal = J Thorac Cardiovasc Surg | volume = 130 | issue = 1 | pages = 160-5 | month = Jul | year = 2005 | doi = 10.1016/j.jtcvs.2004.11.021 | PMID = 15999057 }}</ref>
'''Pleural invasion''' is the presence of tumour in the [[pleura]]. Pleural invasion is poor prognosticator in [[lung cancer]],<ref name=pmid19057261>{{Cite journal  | last1 = Travis | first1 = WD. | last2 = Brambilla | first2 = E. | last3 = Rami-Porta | first3 = R. | last4 = Vallières | first4 = E. | last5 = Tsuboi | first5 = M. | last6 = Rusch | first6 = V. | last7 = Goldstraw | first7 = P. | title = Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer. | journal = J Thorac Oncol | volume = 3 | issue = 12 | pages = 1384-90 | month = Dec | year = 2008 | doi = 10.1097/JTO.0b013e31818e0d9f | PMID = 19057261 }}</ref><ref name=pmid15999057>{{Cite journal  | last1 = Shimizu | first1 = K. | last2 = Yoshida | first2 = J. | last3 = Nagai | first3 = K. | last4 = Nishimura | first4 = M. | last5 = Ishii | first5 = G. | last6 = Morishita | first6 = Y. | last7 = Nishiwaki | first7 = Y. | title = Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer. | journal = J Thorac Cardiovasc Surg | volume = 130 | issue = 1 | pages = 160-5 | month = Jul | year = 2005 | doi = 10.1016/j.jtcvs.2004.11.021 | PMID = 15999057 }}</ref> and important in determining the Tumour stage.


The visceral pleura is the pleura that covers the [[lung]]; tumour invasion into it is known as '''visceral pleural invasion''' (abbreviated '''VPI'''). The parietal pleural covers the chest wall.
The visceral pleura is the pleura that covers the [[lung]]; tumour invasion into it is known as '''visceral pleural invasion''' (abbreviated '''VPI'''). The parietal pleural covers the chest wall.

Revision as of 15:27, 31 August 2015

Pleural invasion is the presence of tumour in the pleura. Pleural invasion is poor prognosticator in lung cancer,[1][2] and important in determining the Tumour stage.

The visceral pleura is the pleura that covers the lung; tumour invasion into it is known as visceral pleural invasion (abbreviated VPI). The parietal pleural covers the chest wall.

Modified Hammar classification

Can be subgrouped:[1]

Category Description Tumour stage (TNM staging)
PL0 tumour confined to lung, not through elastic layer T(any)
PL1 tumour beyond elastic layer of the visercal pleura, not at pleural surface at least T2
PL2 tumour at surface of pleura, not in parietal pleura at least T2
PL3 tumour within parietal pleura and visceral pleura at least T3

See also

References

  1. 1.0 1.1 Travis, WD.; Brambilla, E.; Rami-Porta, R.; Vallières, E.; Tsuboi, M.; Rusch, V.; Goldstraw, P. (Dec 2008). "Visceral pleural invasion: pathologic criteria and use of elastic stains: proposal for the 7th edition of the TNM classification for lung cancer.". J Thorac Oncol 3 (12): 1384-90. doi:10.1097/JTO.0b013e31818e0d9f. PMID 19057261.
  2. Shimizu, K.; Yoshida, J.; Nagai, K.; Nishimura, M.; Ishii, G.; Morishita, Y.; Nishiwaki, Y. (Jul 2005). "Visceral pleural invasion is an invasive and aggressive indicator of non-small cell lung cancer.". J Thorac Cardiovasc Surg 130 (1): 160-5. doi:10.1016/j.jtcvs.2004.11.021. PMID 15999057.