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Difference between revisions of "Placental site nodule"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Placental site nodule -- very high mag.jpg | |||
| Width = | |||
| Caption = Placental site nodule. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = paucicellular hyaline material scattered cells (variable cell population: small to large cells with clear to eosinophilic cytoplasm), +/-multinucleation, no mitotic activity | |||
| Subtypes = | |||
| LMDDx = invasive [[cervical squamous cell carcinoma]], [[exaggerated placental site]], fibrin +/-inflammatory cells | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[endometrium]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = previously pregnant | |||
| Signs = | |||
| Symptoms = none | |||
| Prevalence = common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = none | |||
}} | |||
'''Placental site nodule''', abbreviated '''PSN''', is a benign remnant of a [[placenta]]. It is seen on [[endometrium|endometrial]] biopsies and hysterectomy specimens. | '''Placental site nodule''', abbreviated '''PSN''', is a benign remnant of a [[placenta]]. It is seen on [[endometrium|endometrial]] biopsies and hysterectomy specimens. | ||
'''Implantation site''' redirects here. | |||
==General== | ==General== | ||
*Benign. | *Benign. | ||
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*[[Exaggerated placental site]]. | *[[Exaggerated placental site]]. | ||
**Different histomorphology than PSN; EPS:<ref name=pmid19332926/> syncytiotrophoblastic tissue, in cords/nests, no hyaline nodules. | **Different histomorphology than PSN; EPS:<ref name=pmid19332926/> syncytiotrophoblastic tissue, in cords/nests, no hyaline nodules. | ||
*Fibrin +/-inflammatory cells. | |||
===Images=== | ===Images=== | ||
====Case 1==== | |||
<gallery> | <gallery> | ||
Image:Placental_site_nodule_-_intermed_mag.jpg | PSN - intermed. mag. (WC) | Image:Placental_site_nodule_-_intermed_mag.jpg | PSN - intermed. mag. (WC) | ||
Image:Placental_site_nodule_-_high_mag.jpg | PSN - high mag. (WC) | Image:Placental_site_nodule_-_high_mag.jpg | PSN - high mag. (WC) | ||
</gallery> | </gallery> | ||
www | ====Case 2==== | ||
<gallery> | |||
Image: Placental site nodule -- low mag.jpg | PSN - low mag. | |||
Image: Placental site nodule -- intermed mag.jpg | PSN - intermed. mag. | |||
Image: Placental site nodule -- high mag.jpg | PSN - high mag. | |||
Image: Placental site nodule -- very high mag.jpg | PSN - very high mag. | |||
</gallery> | |||
====www==== | |||
*[http://www.ijpmonline.org/viewimage.asp?img=IndianJPatholMicrobiol_2009_52_2_240_48931_u4.jpg PSN (ijpmonline.org)].<ref name=pmid19332926/> | *[http://www.ijpmonline.org/viewimage.asp?img=IndianJPatholMicrobiol_2009_52_2_240_48931_u4.jpg PSN (ijpmonline.org)].<ref name=pmid19332926/> | ||
*[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=12&cat3=1256&stype=d PSN (gfmer.ch)] - includes images from ''Jacob and Mohapatra''.<ref name=pmid19332926/> | *[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=12&cat3=1256&stype=d PSN (gfmer.ch)] - includes images from ''Jacob and Mohapatra''.<ref name=pmid19332926/> | ||
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==See also== | ==See also== | ||
*[[Gestational trophoblastic disease]]. | *[[Gestational trophoblastic disease]]. | ||
*[[Endometrium]]. | |||
==References== | ==References== | ||
{{Reflist|1}} | {{Reflist|1}} | ||
[[Category:Gestational trophoblastic disease]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Endometrium]] | |||