Placenta creta

From Libre Pathology
Revision as of 19:56, 17 June 2014 by Michael (talk | contribs) (split out)
Jump to navigation Jump to search

Placenta creta is an uncommon pathology of placental attachment.

General

  • What?
    • Trophoblastic tissue deeper than it should be.
  • Clinical?
    • Postpartum hemorrhage leading to a hysterectomy.[1]
  • Pathogenesis?
    • It is suspected that it arises as there is defect in the endometrium/myometrium -- not deep trophoblastic invasion.[1]
    • Risk factors:[2]
      • Placenta previa.
      • Previous caesarian section.

Note:

  • Normal: trophoblastic tissue attaches to the decidua.[3]
  • Retained placentas have less multinucleated trophoblastic giant cells.[4]

Placenta accreta

  • Trophoblastic tissue (directly) adherent to the myometrium.[3]

Image:

Placenta increta

  • Trophoblastic tissue extends into the myometrium.

Placenta percreta

  • Trophoblastic tissue penetrates through the myometrium.

See also

References

  1. 1.0 1.1 Tantbirojn, P.; Crum, CP.; Parast, MM. (Jul 2008). "Pathophysiology of placenta creta: the role of decidua and extravillous trophoblast.". Placenta 29 (7): 639-45. doi:10.1016/j.placenta.2008.04.008. PMID 18514815.
  2. Wortman, AC.; Alexander, JM. (Mar 2013). "Placenta accreta, increta, and percreta.". Obstet Gynecol Clin North Am 40 (1): 137-54. doi:10.1016/j.ogc.2012.12.002. PMID 23466142.
  3. 3.0 3.1 Böcker, Werner; Denk, Helmut; Heitz, Philipp U.; Moch, Holger (2008). [Pathologie] (4th ed.). Urban & Fischer Verlag/Elsevier GmbH. pp. 974. ISBN 978-3437423826.
  4. van Beekhuizen, HJ.; Joosten, I.; de Groot, AN.; Lotgering, FK.; van der Laak, J.; Bulten, J. (Sep 2009). "The number of multinucleated trophoblastic giant cells in the basal decidua is decreased in retained placenta.". J Clin Pathol 62 (9): 794-7. doi:10.1136/jcp.2009.065953. PMID 19734475.
  5. URL: http://library.med.utah.edu/WebPath/EXAM/IMGQUIZ/plfrm.html. Accessed on: 3 December 2011.