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Difference between revisions of "Placenta"
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→Fetal thrombotic vasculopathy: +images
(→Fetal thrombotic vasculopathy: +images) |
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==Fetal thrombotic vasculopathy== | ==Fetal thrombotic vasculopathy== | ||
===General=== | ===General=== | ||
*May cause IUGR. | *May cause [[IUGR]]. | ||
*Associated with cerebral palsy and common in perinatal deaths.<ref name=pmid10414494>{{cite journal |author=Kraus FT, Acheen VI |title=Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy |journal=Hum. Pathol. |volume=30 |issue=7 |pages=759–69 |year=1999 |month=July |pmid=10414494 |doi= |url=}}</ref> | *Associated with cerebral palsy and common in perinatal deaths.<ref name=pmid10414494>{{cite journal |author=Kraus FT, Acheen VI |title=Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy |journal=Hum. Pathol. |volume=30 |issue=7 |pages=759–69 |year=1999 |month=July |pmid=10414494 |doi= |url=}}</ref> | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=pmid10414494>{{Cite journal | last1 = Kraus | first1 = FT. | last2 = Acheen | first2 = VI. | title = Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy. | journal = Hum Pathol | volume = 30 | issue = 7 | pages = 759-69 | month = Jul | year = 1999 | doi = | PMID = 10414494 }}</ref> | ||
*Thrombus in the fetal vasculature +/- recanalization. | *Thrombus in the fetal vasculature +/- recanalization. | ||
**Eosinophilic (light pink on H&E), moderately granular intravascular material (fibrin) with layering. | **Eosinophilic (light pink on H&E), moderately granular intravascular material (fibrin) with layering. | ||
*Clustered fibrotic villi without blood vessels - '''key feature'''. | |||
**This is a chronic change. | |||
Images: | Images: | ||
*[http://jcp.bmj.com/content/61/12/1254/F8.large.jpg FTV (bmj.com)].<ref>URL: [http://jcp.bmj.com/content/61/12/1254.abstract http://jcp.bmj.com/content/61/12/1254.abstract]. Accessed on: 12 January 2011.</ref> | *www: | ||
*[http://gut.bmj.com/content/41/3/354/F3.large.jpg Thrombus - rat (bmj.com)].<ref>URL: [http://gut.bmj.com/content/41/3/354.full http://gut.bmj.com/content/41/3/354.full]. Accessed on: 12 January 2011.</ref> | **[http://jcp.bmj.com/content/61/12/1254/F8.large.jpg FTV (bmj.com)].<ref>URL: [http://jcp.bmj.com/content/61/12/1254.abstract http://jcp.bmj.com/content/61/12/1254.abstract]. Accessed on: 12 January 2011.</ref> | ||
**[http://gut.bmj.com/content/41/3/354/F3.large.jpg Thrombus - rat (bmj.com)].<ref>URL: [http://gut.bmj.com/content/41/3/354.full http://gut.bmj.com/content/41/3/354.full]. Accessed on: 12 January 2011.</ref> | |||
*[[WC]]: | |||
**[http://commons.wikimedia.org/wiki/File:Fetal_thrombotic_vasculopathy_-_intermed_mag.jpg FTV - intermed. mag. (WC)]. | |||
**[http://commons.wikimedia.org/wiki/File:Fetal_thrombotic_vasculopathy_-_high_mag.jpg FTV - high mag. (WC)]. | |||
==Hemorrhagic endovasculitis== | ==Hemorrhagic endovasculitis== | ||