Pityriasis rubra pilaris

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Pityriasis rubra pilaris
Diagnosis in short
Site skin - see inflammatory skin disorders

Prevalence uncommon

Pityriasis rubra pilaris, abbreviated PRP, is an uncommon inflammatory skin disorder.

General

  • Uncommon.[1]
  • Typically sporadic, may be familial.[2]
  • Bimodal age distribution:[3]
    • Children: <10 years.
    • Adults: 40s and 50s.

Treatment:

  • Retinoids, methotrexate and others.[3]

Gross

  • Salmon-coloured (red) plaques interrupted by well-demarcated normal appearing skin.[3]

Microscopic

Features:[1]

Images

Stains

IHC

Molecular

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See also

References

  1. 1.0 1.1 Marrouche, N.; Kurban, M.; Kibbi, AG.; Abbas, O. (Apr 2014). "Pityriasis rubra pilaris: clinicopathological study of 32 cases from Lebanon.". Int J Dermatol 53 (4): 434-9. PMID 24783259.
  2. Mercer, JM.; Pushpanthan, C.; Anandakrishnan, C.; Landells, ID.. "Familial pityriasis rubra pilaris: case report and review.". J Cutan Med Surg 17 (4): 226-32. PMID 23815954.
  3. 3.0 3.1 3.2 Klein, A.; Landthaler, M.; Karrer, S. (2010). "Pityriasis rubra pilaris: a review of diagnosis and treatment.". Am J Clin Dermatol 11 (3): 157-70. doi:10.2165/11530070-000000000-00000. PMID 20184391.
  4. 4.0 4.1 4.2 Leger, M.; Newlove, T.; Robinson, M.; Patel, R.; Meehan, S.; Ramachandran, S. (Dec 2012). "Pityriasis rubra pilaris.". Dermatol Online J 18 (12): 14. PMID 23286804.