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Difference between revisions of "Pityriasis rubra pilaris"
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Pityriasis rubra pilaris (view source)
Revision as of 04:51, 30 September 2014
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*Occasional mild spongiosis. | *Occasional mild spongiosis. | ||
Notes: | |||
*PRP is easy to miss - clinical history (r/o PRP) usually needed to prompt correct diagnosis. | *PRP is easy to miss - clinical history (r/o PRP) usually needed to prompt correct diagnosis. | ||
*Psoriasis vulgaris <ref name=pmid18418089>{{Cite journal | last1 = Brinster | first1 = NK. | title = Dermatopathology for the surgical pathologist: a pattern based approach to the diagnosis of inflammatory skin disorders (part I). | journal = Adv Anat Pathol | volume = 15 | issue = 2 | pages = 76-96 | month = Mar | year = 2008 | doi = 10.1097/PAP.0b013e3181664e8d | PMID = 18418089 }}</ref> - thinned suprapapillary plates, hypogranulosis, neutrophils in the stratum corneum, dilated papillary dermal blood vessels, acantholysis absent | |||
*Lichen simplex chronicus - usually a localized process, not a widespread process. | ===Microscopic DDx=== | ||
*[[Psoriasis vulgaris]]<ref name=pmid18418089>{{Cite journal | last1 = Brinster | first1 = NK. | title = Dermatopathology for the surgical pathologist: a pattern based approach to the diagnosis of inflammatory skin disorders (part I). | journal = Adv Anat Pathol | volume = 15 | issue = 2 | pages = 76-96 | month = Mar | year = 2008 | doi = 10.1097/PAP.0b013e3181664e8d | PMID = 18418089 }}</ref> - thinned suprapapillary plates, hypogranulosis, neutrophils in the stratum corneum, dilated papillary dermal blood vessels, acantholysis absent. | |||
*[[Lichen simplex chronicus]] - usually a localized process, not a widespread process. | |||
*Darier disease - acantholysis is prominent with corps ronds and grains, follicular plugging absent. | *Darier disease - acantholysis is prominent with corps ronds and grains, follicular plugging absent. | ||
*Pemphigus vulgaris - PRP with extensive acantholysis | *[[Pemphigus vulgaris]] - PRP with extensive acantholysis can mimic; [[immunofluorescence|IF]] will be negative in PRP. | ||
*Hailey-Hailey - | *[[Hailey-Hailey disease]] - falling brick wall pattern of acantholysis. | ||
*Seborrhoeic dermatitis - more spongiotic, often with neutrophils. | *Seborrhoeic dermatitis - more spongiotic, often with neutrophils. | ||
*[[ | *[[Dermatophytosis|Fungal infection]]. | ||
==Associated Diagnoses== | ==Associated Diagnoses== | ||