Difference between revisions of "Peripheral nerve sheath tumours"

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(→‎Neurofibroma: re-work)
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==Neurofibroma==
==Neurofibroma==
===General===
===General===
*May be a part of [[neurofibromatosis]] 1.
*May be a part of [[neurofibromatosis]] 1 (NF1).
*Composed of Schwann cells, axons, fibrous material.<ref name=pmid17893219/>
*Composed of Schwann cells, axons, fibrous material.<ref name=pmid17893219/>
Classification:<ref name=pmid15486243>{{Cite journal  | last1 = Wilkinson | first1 = LM. | last2 = Manson | first2 = D. | last3 = Smith | first3 = CR. | title = Best cases from the AFIP: plexiform neurofibroma of the bladder. | journal = Radiographics | volume = 24 Suppl 1 | issue =  | pages = S237-42 | month = Oct | year = 2004 | doi = 10.1148/rg.24si035170 | PMID = 15486243 }}</ref>
#Localized - sporatic.
#Diffuse - usu. poorly defined, young adults and children; sporatic.
#Plexiform - assoc. with NF1.
===Gross/radiologic===
Gross features (plexiform NF):<ref name=pmid15486243>{{Cite journal  | last1 = Wilkinson | first1 = LM. | last2 = Manson | first2 = D. | last3 = Smith | first3 = CR. | title = Best cases from the AFIP: plexiform neurofibroma of the bladder. | journal = Radiographics | volume = 24 Suppl 1 | issue =  | pages = S237-42 | month = Oct | year = 2004 | doi = 10.1148/rg.24si035170 | PMID = 15486243 }}</ref>
*"Bag of worms" appearance.
Radiologic:<ref name=pmid15486243/>
*Fusiform mass.


===Microscopic===
===Microscopic===
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Image:  
Image:  
*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(1).jpg Neurofibroma - low mag. (WC)].
*[[WC]]:
*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(2).jpg Neurofibroma - high mag. (WC)].
**[http://commons.wikimedia.org/wiki/File:Neurofibroma_(1).jpg Neurofibroma - low mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Neurofibroma_(3).jpg Neurofibroma - high mag. (WC)].
**[http://commons.wikimedia.org/wiki/File:Neurofibroma_(2).jpg Neurofibroma - high mag. (WC)].
**[http://commons.wikimedia.org/wiki/File:Neurofibroma_(3).jpg Neurofibroma - high mag. (WC)].
www:
*[http://radiographics.rsna.org/content/24/suppl_1/S237/F9.expansion.html Plexiform neurofibroma (rsna.org)].
*[http://radiographics.rsna.org/content/24/suppl_1/S237/F10.expansion.html Plexiform neurofibroma (rsna.org)].


===IHC===
===IHC===
48,460

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