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Difference between revisions of "Pediatric-type diffuse low-grade glioma"
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Pediatric-type diffuse low-grade glioma (view source)
Revision as of 09:48, 5 April 2022
, 09:48, 5 April 2022MAPK-altered entity added
Jensflorian (talk | contribs) (New WHO category 2021) |
Jensflorian (talk | contribs) (MAPK-altered entity added) |
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=Diffuse low-grade glioma, MAPK pathway-altered= | =Diffuse low-grade glioma, MAPK pathway-altered= | ||
* Since 2021 official WHO entity. | |||
* Astrocytic or oligodendroglial morphology. | |||
* Mostly in the cerebral hemispheres. | |||
* Commonly associated with epilepsy. | |||
* Olig2-ve, GFAP variable, CD34 mostly absent. | |||
* IDH and HF3FA mutations and CDKN2A deletions not compatible with this diagnosis. | |||
* Mutations in BRAF (V600E), FGFR1 or duplication in FGFR1 TKD. | |||