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Difference between revisions of "Pediatric-type diffuse high-grade glioma"
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Pediatric-type diffuse high-grade glioma (view source)
Revision as of 10:22, 5 April 2022
, 10:22, 5 April 2022→Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype: add last entity
Jensflorian (talk | contribs) (+ Infant-type hemispheric glioma) |
Jensflorian (talk | contribs) (→Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype: add last entity) |
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=Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype= | =Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype= | ||
* CNS WHO grade 4 tumour ocurring in children and adolescents. | |||
* May occur anywhere in the brain. | |||
* Contrast enhancing tumour. | |||
* Frequent alterations include TP53, PDGFRA, EGFR or MYCN. | |||
* Absence of IDH1/2 and H3F3a mutation. | |||
* Three distinct subtypes in methylation profile. | |||
=Infant-type hemispheric glioma= | =Infant-type hemispheric glioma= | ||