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Difference between revisions of "Papillary urothelial neoplasm of low malignant potential"
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Papillary urothelial neoplasm of low malignant potential (view source)
Revision as of 19:40, 19 April 2022
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'''PUNLMP''' is pronounced ''pun-lump''. | '''PUNLMP''' is pronounced ''pun-lump''. | ||
''Inverted urothelial neoplasm of low malignant potential'' (abbreviated ''IUNLMP'') redirects here. | |||
==General== | ==General== | ||
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*Infrequent mitoses. | *Infrequent mitoses. | ||
*Nuclei larger than papilloma - but monotonous.<ref name=Ref_GUP170>{{Ref GUP|170}}</ref> | *Nuclei larger than papilloma - but monotonous.<ref name=Ref_GUP170>{{Ref GUP|170}}</ref> | ||
Note: | |||
*May grow downward; known as ''PUNLMP with inverted growth''<ref name=pmid25886613>{{Cite journal | last1 = Maxwell | first1 = JP. | last2 = Wang | first2 = C. | last3 = Wiebe | first3 = N. | last4 = Yilmaz | first4 = A. | last5 = Trpkov | first5 = K. | title = Long-term outcome of primary Papillary Urothelial Neoplasm of Low Malignant Potential (PUNLMP) including PUNLMP with inverted growth. | journal = Diagn Pathol | volume = 10 | issue = | pages = 3 | month = | year = 2015 | doi = 10.1186/s13000-015-0234-z | PMID = 25886613 }}</ref> and ''inverted urothelial neoplasm of low malignant potential'' (abbreviated ''IUNLMP'').<ref name=pmid21122976>{{Cite journal | last1 = Montironi | first1 = R. | last2 = Cheng | first2 = L. | last3 = Lopez-Beltran | first3 = A. | last4 = Scarpelli | first4 = M. | last5 = Mazzucchelli | first5 = R. | last6 = Mikuz | first6 = G. | last7 = Kirkali | first7 = Z. | last8 = Montorsi | first8 = F. | title = Inverted (endophytic) noninvasive lesions and neoplasms of the urothelium: the Cinderella group has yet to be fully exploited. | journal = Eur Urol | volume = 59 | issue = 2 | pages = 225-30 | month = Feb | year = 2011 | doi = 10.1016/j.eururo.2010.11.018 | PMID = 21122976 }}</ref> | |||
DDx: | DDx: | ||
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<gallery> | <gallery> | ||
Image:Punlmp1.jpg | PUNLMP - low mag. (WC/Nephron) | Image:Punlmp1.jpg | PUNLMP - low mag. (WC/Nephron) | ||
Image: | Image:Punlmp2.jpg | PUNLMP - high mag. (WC/Nephron) | ||
</gallery> | </gallery> | ||
==Sign out== | |||
<pre> | |||
Urinary Bladder Tumour, Transurethral Resection: | |||
- Papillary urothelial neoplasm of low malignant potential (PUNLMP). | |||
</pre> | |||
===Micro=== | |||
The sections show a papillary urothelial lesion with minimal anisonucleosis. The papillae are predominantly slender and branch. Minimal proliferative activity is present. The lesion is well demarcated in relation to the subepithelial tissue. | |||
====Alternate==== | |||
The sections show a papillary urothelial lesion with monotonous nuclei and minimal atypia. The papillae are predominantly slender and branch. Mitotic figures are very rare. The lesion is well demarcated in relation to the subepithelial tissue. | |||
===Inverted pattern predominant=== | |||
<pre> | |||
Urinary Bladder Tumour, Transurethral Resection: | |||
- Inverted urothelial neoplasm of low malignant potential with an | |||
exophytic papillary component. | |||
Comment: | |||
This lesion is a variant of papillary urothelial neoplasm of low malignant | |||
potential (PUNLMP). Followup is required. | |||
The case was reviewed by a second GU pathologist. | |||
</pre> | |||
==See also== | ==See also== | ||