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'''Pankeratin''', also '''pancytokeratin''', refers to an immunostain that markers abroad array of keratins. | [[Image:Prostate carcinoma with inflammation - panker -- low mag.jpg|right|thumb|350px|Pankeratin immunostain showing benign prostatic glands (left of image) and [[prostatic carcinoma]] (right of image).]] | ||
'''Pankeratin''' (abbreviated '''panker'''), also known as '''pancytokeratin''', refers to an [[immunostain]] that markers abroad array of keratins. | |||
''Keratin'' may be used as a synonym for ''pankeratin''. A general discussion about different types of ''keratins'' is found in the ''[[keratins]]'' article. | |||
==Overview== | |||
Several pankeratins exists;<ref name=pmid10975928>{{Cite journal | last1 = Xu | first1 = X. | last2 = Roberts | first2 = SA. | last3 = Pasha | first3 = TL. | last4 = Zhang | first4 = PJ. | title = Undesirable cytokeratin immunoreactivity of native nonepithelial cells in sentinel lymph nodes from patients with breast carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 9 | pages = 1310-3 | month = Sep | year = 2000 | doi = 10.1043/0003-9985(2000)124<1310:UCIONN>2.0.CO;2 | PMID = 10975928 }}</ref> thus, ''pankeratin'' as a descriptor is not very specific. | Several pankeratins exists;<ref name=pmid10975928>{{Cite journal | last1 = Xu | first1 = X. | last2 = Roberts | first2 = SA. | last3 = Pasha | first3 = TL. | last4 = Zhang | first4 = PJ. | title = Undesirable cytokeratin immunoreactivity of native nonepithelial cells in sentinel lymph nodes from patients with breast carcinoma. | journal = Arch Pathol Lab Med | volume = 124 | issue = 9 | pages = 1310-3 | month = Sep | year = 2000 | doi = 10.1043/0003-9985(2000)124<1310:UCIONN>2.0.CO;2 | PMID = 10975928 }}</ref> thus, ''pankeratin'' as a descriptor is not very specific. | ||
==Examples of specific pankeratins== | |||
*Pan CK clone 5D3.<ref name=pmid10975928/> | |||
*Pan CK clone LP34.<ref name=pmid10975928/> | |||
*[[AE1/AE3]].<ref name=pmid10975928/> | |||
==See also== | ==See also== | ||
*[[Immunohistochemistry]]. | *[[Immunohistochemistry]]. | ||
*[[EMA]]. | |||
*[[AE1/AE3]]. | |||
==References== | ==References== | ||