Difference between revisions of "Pancreas"

Pancreas (view source)

96 bytes added , 19:45, 26 May 2010

48,466

edits

@@ Line 280: / Line 280: @@
 *Prognosis of m. cystadenocarcinoma is slightly better than that of ductal adenocarcinoma.
-==IPMT==
+==Intraductal papillary mucinous tumour==
-Intraductal papillary mucinous tumour (IPMT)
+===General===
+*Often abbreviated ''IPMT''.
 *Papillomatous growth pattern.
 *Morphologically and biologically distinct from ductal adenocarcinoma, mucinous cystic tumour and ductal papillary hyperplasia.
+===Epidemiology===
 *1% of all exocrine pancreatic tumours.
 *More common in males.
 *Mean age at presentation 62 years.
-*60-80% occur in the head of the pancreas
+*60-80% occur in the head of the pancreas.
-*average size 4 cm
+*Average size 4 cm.
 Khalifa's theory:
 *Nothing but dilation of pancreatic duct + hypersecretion.
-Gross
+====Adenoma-carcinoma sequence====
-*May be patchy/multifocal.
+Hyperplasia.
+#Adenomatous hyperplasia.
+#Carcinoma in situ.
+#Invasive carcinoma.
-===Sequence===
+Note: K-ras oncogene mutation associated - seen in all stages of the sequence.
-*Hyperplasia.
-*Adenomatous hyperplasia.
-*Carcinoma in situ.
-*Invasive carcinoma.
-K-ras oncogene muation associated - seen in all stages of the sequence.
+===Gross===
+*May be patchy/multifocal.
-Characteristics
+===Microscopic===
+Features
 *Cell enlargement.
 *Incr. NC ratio.
@@ Line 312: / Line 316: @@
 *Increased mucin production.
-===classification IMPT===
+===Classification IMPT===
 *Adenoma.
 *Borderline mucinous tumour.
 *Carcinoma.
 NB1