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Difference between revisions of "Pancreas"
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→Ductal adenocarcinoma: more
(→Ductal adenocarcinoma: more) |
(→Ductal adenocarcinoma: more) |
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**15% in the body, 5% tail, 20% diffuse (head, body & tail).<ref name=Ref_PBoD950>{{Ref PBoD|950}}</ref> | **15% in the body, 5% tail, 20% diffuse (head, body & tail).<ref name=Ref_PBoD950>{{Ref PBoD|950}}</ref> | ||
*Abysmal prognosis. | *Abysmal prognosis. | ||
Molecular characteristics:<ref name=Ref_PCPBoD8_470-1>{{Ref PCPBoD|470-1}}</ref> | |||
*KRAS (oncogene) mutation in ~ 90% of cases. | |||
*CDKN2A<ref name=omim600160>{{OMIM|600160}}</ref> (tumour suppressor) inactivation ~ 95% of cases. | |||
**[[AKA]] p16. | |||
===Microscopic=== | ===Microscopic=== | ||