Difference between revisions of "Pancreas"

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190 bytes added ,  13:27, 29 May 2010
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*Prognosis: favourable, if caught earlier; not much different than ductal adenocarcinoma if caught later.<ref name=pmid12377813>{{cite journal |author=Maire F, Hammel P, Terris B, ''et al.'' |title=Prognosis of malignant intraductal papillary mucinous tumours of the pancreas after surgical resection. Comparison with pancreatic ductal adenocarcinoma |journal=Gut |volume=51 |issue=5 |pages=717–22 |year=2002 |month=November |pmid=12377813 |pmc=1773420 |doi= |url=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12377813}}</ref>
*Prognosis: favourable, if caught earlier; not much different than ductal adenocarcinoma if caught later.<ref name=pmid12377813>{{cite journal |author=Maire F, Hammel P, Terris B, ''et al.'' |title=Prognosis of malignant intraductal papillary mucinous tumours of the pancreas after surgical resection. Comparison with pancreatic ductal adenocarcinoma |journal=Gut |volume=51 |issue=5 |pages=717–22 |year=2002 |month=November |pmid=12377813 |pmc=1773420 |doi= |url=http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=12377813}}</ref>


Another paper: <ref>{{cite journal |author=Baiocchi GL, Portolani N, Missale G, ''et al.'' |title=Intraductal papillary mucinous neoplasm of the pancreas (IPMN): clinico-pathological correlations and surgical indications |journal=World J Surg Oncol |volume=8 |issue= |pages=25 |year=2010 |pmid=20374620 |pmc=2858722 |doi=10.1186/1477-7819-8-25 |url=http://wjso.com/content/8/1/25}}</re>
===Epidemiology===
===Epidemiology===
*1% of all exocrine pancreatic tumours.
*1% of all exocrine pancreatic tumours.
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Khalifa's theory:
Khalifa's theory:
*Nothing but dilation of pancreatic duct + hypersecretion.
*Nothing but dilation of pancreatic duct + hypersecretion.
====Adenoma-carcinoma sequence====
#Hyperplasia.
#Adenomatous hyperplasia.
#Carcinoma in situ.
#Invasive carcinoma.
Note: K-ras oncogene mutation associated - seen in all stages of the sequence.


===Gross===
===Gross===
48,470

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