Difference between revisions of "Ovarian tumours"

Ovarian tumours (view source)

1,336 bytes removed , 23:45, 18 October 2014

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 ===Gross===
 *Classically solid.
-===Microscopic===
-Features:
-* Classic appearance includes gland-like structures filled with acidophilic material (Call-Exner bodies).
-* Small cuboidal to polygonal cell in sheets ''or'' strands ''or'' cords.
-* Nuclear grooves.
-Note:
-*There is a "10% rule" -- if less than 10% of a SCST is granulosa cells... it isn't granulosa cell tumour.
-*Juvenile variant of GCT has more nuclear pleomorphism.
-DDx:<ref>{{Cite journal  | last1 = Kommoss | first1 = S. | last2 = Anglesio | first2 = MS. | last3 = Mackenzie | first3 = R. | last4 = Yang | first4 = W. | last5 = Senz | first5 = J. | last6 = Ho | first6 = J. | last7 = Bell | first7 = L. | last8 = Lee | first8 = S. | last9 = Lorette | first9 = J. | title = FOXL2 molecular testing in ovarian neoplasms: diagnostic approach and procedural guidelines. | journal = Mod Pathol | volume = 26 | issue = 6 | pages = 860-7 | month = Jun | year = 2013 | doi = 10.1038/modpathol.2012.226 | PMID = 23348906 }}</ref>
-* [[Urothelial cell carcinoma]] (UCC).
-** UCC usually has extensive necrosis.
-* [[Brenner tumour]].
-* [[Sertoli cell tumour]].
-* [[Sertoli-Leydig cell tumour]].
-* [[Endometrial stromal sarcoma]].
-====Images====
-<gallery>
-Image:Granulosa_cell_tumour1.jpg | Granulosa cell tumour - low mag. (WC)
-Image:Granulosa_cell_tumour2.jpg | Granulosa cell tumour - high mag. (WC)
-</gallery>
 ===IHC===