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Difference between revisions of "Ovarian tumours"
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→Metastatic ovarian tumours: +IHC
(→Metastatic ovarian tumours: +IHC) |
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===Mucinous carcinoma - [[GI tract]] metastasis vs. primary ovarian=== | ===Mucinous carcinoma - [[GI tract]] metastasis vs. primary ovarian=== | ||
====Gross==== | |||
Features favouring metastatic disease:<ref name=pmid18162780>{{Cite journal | last1 = Yemelyanova | first1 = AV. | last2 = Vang | first2 = R. | last3 = Judson | first3 = K. | last4 = Wu | first4 = LS. | last5 = Ronnett | first5 = BM. | title = Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary site with reevaluation of an algorithm for tumor classification. | journal = Am J Surg Pathol | volume = 32 | issue = 1 | pages = 128-38 | month = Jan | year = 2008 | doi = 10.1097/PAS.0b013e3180690d2d | PMID = 18162780 }}</ref> | Features favouring metastatic disease:<ref name=pmid18162780>{{Cite journal | last1 = Yemelyanova | first1 = AV. | last2 = Vang | first2 = R. | last3 = Judson | first3 = K. | last4 = Wu | first4 = LS. | last5 = Ronnett | first5 = BM. | title = Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary site with reevaluation of an algorithm for tumor classification. | journal = Am J Surg Pathol | volume = 32 | issue = 1 | pages = 128-38 | month = Jan | year = 2008 | doi = 10.1097/PAS.0b013e3180690d2d | PMID = 18162780 }}</ref> | ||
*Bilaterality -- both ovaries involved. | *Bilaterality -- both ovaries involved. | ||
*Small unilateral tumour size -- <10 cm = metastatic. | *Small unilateral tumour size -- <10 cm = metastatic. | ||
**>13 cm = primary ovarian. | **>13 cm = primary ovarian. | ||
====IHC==== | |||
Ovarian tumours: | |||
*Dipeptidase 1 (DPEP1) +ve.<ref name=pmid21076463>{{Cite journal | last1 = Okamoto | first1 = T. | last2 = Matsumura | first2 = N. | last3 = Mandai | first3 = M. | last4 = Oura | first4 = T. | last5 = Yamanishi | first5 = Y. | last6 = Horiuchi | first6 = A. | last7 = Hamanishi | first7 = J. | last8 = Baba | first8 = T. | last9 = Koshiyama | first9 = M. | title = Distinguishing primary from secondary mucinous ovarian tumors: an algorithm using the novel marker DPEP1. | journal = Mod Pathol | volume = 24 | issue = 2 | pages = 267-76 | month = Feb | year = 2011 | doi = 10.1038/modpathol.2010.204 | PMID = 21076463 }}</ref> | |||
*CK7 +ve. | |||
=Sex cord stromal tumours= | =Sex cord stromal tumours= | ||