Difference between revisions of "Ovarian tumours"

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675 bytes added ,  13:27, 10 October 2011
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===General===
===General===
*Sertoli and leydig cells are normal in the [[testis]].
*Sertoli and leydig cells are normal in the [[testis]].
*Poorly differentiated tumours have sarcomatous features.<ref name=Ref_PBoD1103>{{Ref PBoD|1103}}</ref>


===Microscopic===
===Microscopic===
Features:<ref name=Ref_PBoD1103>{{Ref PBoD|1103}}</ref>
Features:
* Tubules with Sertoli or Leydig cells + stroma.  
# Sertoli ''or'' Leydig cells.<ref name=Ref_PBoD1103>{{Ref PBoD|1103}}</ref>  
* +/- Sarcomatous features (mucinous glands, bone, cartilage).
#* Leydig cells:
#** Abundant solid eosinophilic cytoplasm.
#** Round nuclei with fine chromatin and a small or indistinct [[nucleolus]].
#** Often in small clusters ~ 5-25 cells/cluster.
#* Sertoli cells:
#** Pale/clear vacuolated cytoplasm.
#** Irregular nuclei with irregular/vacuolated-appearing chromatin.
#** Architecture: tubules, cords or sheets.
# Stroma.
# +/- Sarcomatous features (mucinous glands, bone, cartilage).


See: ''[[Sertoli cell tumour]]'', ''[[Leydig cell tumour]]''.
Images:
*[http://commons.wikimedia.org/wiki/File:Sertoli-Leydig_cell_tumour_-_intermed_mag.jpg Sertoli-Leydig cell tumour - intermed. mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Sertoli-Leydig_cell_tumour_-_very_high_mag.jpg Sertoli-Leydig cell tumour - very high mag. (WC)].


==Pure Leydig cell tumour==
==Pure Leydig cell tumour==
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