Difference between revisions of "Oligoastrocytoma"

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#redirect [[Neuropathology tumours#Oligoastrocytoma]]
'''Oligoastrocytoma''' is a rare [[neuropathology tumour]].
 
==General==
*Mixed tumour.
 
==Microscopic==
Features:
*Astrocytoma-like and oligodendroglioma-like:
*#Oligodendroglioma-like cells = round nucleus, peri-nuclear clearing.
*#Astrocytoma-like cells = non-ovoid/elongated nucleus.
 
DDx:
*Anaplastic astrocytoma.
*Oligodendroglioma. (???)
 
===IHC===
*Oligodendroglioma-like cells: MAP-2 +ve (cytoplasm).
*Astrocytoma-like cells: GFAP +ve (cytoplasm, nuclear membrane).
 
Others:
*Ki-67 ~10%. (???)
*p53 - focally +ve. (???)
*IDH-1 +ve. (85%)
 
==See also==
*[[Neuropathology tumours]].
 
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Neuropathology tumours]]

Revision as of 06:51, 10 December 2014

Oligoastrocytoma is a rare neuropathology tumour.

General

  • Mixed tumour.

Microscopic

Features:

  • Astrocytoma-like and oligodendroglioma-like:
    1. Oligodendroglioma-like cells = round nucleus, peri-nuclear clearing.
    2. Astrocytoma-like cells = non-ovoid/elongated nucleus.

DDx:

  • Anaplastic astrocytoma.
  • Oligodendroglioma. (???)

IHC

  • Oligodendroglioma-like cells: MAP-2 +ve (cytoplasm).
  • Astrocytoma-like cells: GFAP +ve (cytoplasm, nuclear membrane).

Others:

  • Ki-67 ~10%. (???)
  • p53 - focally +ve. (???)
  • IDH-1 +ve. (85%)

See also

References