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Difference between revisions of "Olfactory neuroblastoma"
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Olfactory neuroblastoma (view source)
Revision as of 06:53, 22 October 2019
, 06:53, 22 October 2019→IHC: S-100 in neuronal ONB
Jensflorian (talk | contribs) (→Microscopic: Images added) |
Jensflorian (talk | contribs) (→IHC: S-100 in neuronal ONB) |
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==IHC== | ==IHC== | ||
*S-100: | *S-100: | ||
**Small round cells -ve. | |||
**Sustentacular cells +ve. | **Sustentacular cells +ve. | ||
** | ***Neuronal ONB subtype is enriched for the presence of S100 sustentacular cells. | ||
*[[Neuroendocrine markers]] +ve (CD56, synaptophysin). | *[[Neuroendocrine markers]] +ve (CD56, synaptophysin). | ||
**lower expression of neuroendocrine markers in IDH2 mutant tumors. | **lower expression of neuroendocrine markers in IDH2 mutant tumors. | ||