Difference between revisions of "Nuclear pseudoinclusions"

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'''Nuclear pseudoinclusions''', also '''nuclear inclusions''', are things that are found in a number of places.
'''Nuclear pseudoinclusions''' are cytoplasmic invaginations into the nucleus that mimic true nuclear inclusion.


Tumours:
==Nuclear pseudoinclusions and true nuclear inclusions==
True nuclear inclusions consist of material that is:
# Foreign to the nucleus.
# Completely contained within the nucleus.
 
They are classically caused by viral particles; however, there are other causes.<ref name=pmid21081532>{{Cite journal  | last1 = Ip | first1 = YT. | last2 = Dias Filho | first2 = MA. | last3 = Chan | first3 = JK. | title = Nuclear inclusions and pseudoinclusions: friends or foes of the surgical pathologist? | journal = Int J Surg Pathol | volume = 18 | issue = 6 | pages = 465-81 | month = Dec | year = 2010 | doi = 10.1177/1066896910385342 | PMID = 21081532 }}</ref>
 
==Tumours of pseudoinclusions==
*[[Papillary thyroid carcinoma]].
*[[Papillary thyroid carcinoma]].
*[[Medullary thyroid carcinoma]].<ref>URL: [http://www.papsociety.org/guidelines/Morphologic%20criteria.doc http://www.papsociety.org/guidelines/Morphologic%20criteria.doc]. Accessed on: 28 April 2010.</ref>
*[[Medullary thyroid carcinoma]].<ref>URL: [http://www.papsociety.org/guidelines/Morphologic%20criteria.doc http://www.papsociety.org/guidelines/Morphologic%20criteria.doc]. Accessed on: 28 April 2010.</ref>
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*[[Meningioma]].<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm]. Accessed on: 25 October 2010.</ref><ref name=Ref_PSNP194>{{Ref PSNP|194}}</ref>
*[[Meningioma]].<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm]. Accessed on: 25 October 2010.</ref><ref name=Ref_PSNP194>{{Ref PSNP|194}}</ref>


Benign:
==Pseudoinclusions in benign processes==
*[[Arias-Stella reaction]].<ref name=pmid11756756>{{Cite journal  | last1 = Arias-Stella | first1 = J. | title = The Arias-Stella reaction: facts and fancies four decades after. | journal = Adv Anat Pathol | volume = 9 | issue = 1 | pages = 12-23 | month = Jan | year = 2002 | doi =  | PMID = 11756756 }}</ref>
*[[Arias-Stella reaction]].<ref name=pmid11756756>{{Cite journal  | last1 = Arias-Stella | first1 = J. | title = The Arias-Stella reaction: facts and fancies four decades after. | journal = Adv Anat Pathol | volume = 9 | issue = 1 | pages = 12-23 | month = Jan | year = 2002 | doi =  | PMID = 11756756 }}</ref>
**May mimic [[HSV]].<ref name=pmid6284466>{{Cite journal  | last1 = Dardi | first1 = LE. | last2 = Ariano | first2 = L. | last3 = Ariano | first3 = MC. | last4 = Gould | first4 = VE. | title = Arias-Stella reaction with prominent nuclear pseudoinclusions simulating herpetic endometritis. | journal = Diagn Gynecol Obstet | volume = 4 | issue = 2 | pages = 127-32 | month =  | year = 1982 | doi =  | PMID = 6284466 }}</ref>
**May mimic [[HSV]].<ref name=pmid6284466>{{Cite journal  | last1 = Dardi | first1 = LE. | last2 = Ariano | first2 = L. | last3 = Ariano | first3 = MC. | last4 = Gould | first4 = VE. | title = Arias-Stella reaction with prominent nuclear pseudoinclusions simulating herpetic endometritis. | journal = Diagn Gynecol Obstet | volume = 4 | issue = 2 | pages = 127-32 | month =  | year = 1982 | doi =  | PMID = 6284466 }}</ref>

Revision as of 20:59, 16 June 2013

Nuclear pseudoinclusions are cytoplasmic invaginations into the nucleus that mimic true nuclear inclusion.

Nuclear pseudoinclusions and true nuclear inclusions

True nuclear inclusions consist of material that is:

  1. Foreign to the nucleus.
  2. Completely contained within the nucleus.

They are classically caused by viral particles; however, there are other causes.[1]

Tumours of pseudoinclusions

Pseudoinclusions in benign processes

See also

References

  1. Ip, YT.; Dias Filho, MA.; Chan, JK. (Dec 2010). "Nuclear inclusions and pseudoinclusions: friends or foes of the surgical pathologist?". Int J Surg Pathol 18 (6): 465-81. doi:10.1177/1066896910385342. PMID 21081532.
  2. URL: http://www.papsociety.org/guidelines/Morphologic%20criteria.doc. Accessed on: 28 April 2010.
  3. URL: http://moon.ouhsc.edu/kfung/jty1/neurotest/Q51-Ans.htm. Accessed on: 25 October 2010.
  4. Perry, Arie; Brat, Daniel J. (2010). Practical Surgical Neuropathology: A Diagnostic Approach: A Volume in the Pattern Recognition series (1st ed.). Churchill Livingstone. pp. 194. ISBN 978-0443069826.
  5. Arias-Stella, J. (Jan 2002). "The Arias-Stella reaction: facts and fancies four decades after.". Adv Anat Pathol 9 (1): 12-23. PMID 11756756.
  6. Dardi, LE.; Ariano, L.; Ariano, MC.; Gould, VE. (1982). "Arias-Stella reaction with prominent nuclear pseudoinclusions simulating herpetic endometritis.". Diagn Gynecol Obstet 4 (2): 127-32. PMID 6284466.