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Difference between revisions of "Non-specific interstitial pneumonia"
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Non-specific interstitial pneumonia (view source)
Revision as of 18:53, 17 March 2015
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Non-specfic_interstitial_pneumonia_(NSIP),_cellular_variant.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = NSIP. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = diffuse fibrosis (uniform fibrosis (unlike [[UIP]]), +/-''linear fibrosis'' (fibrosis that follows alveolar walls + no architectural distortion), +/-lymphoid nodules (assoc. with collagen vascular disease), +/-focal [[organizing pneumonia]] | | Micro = diffuse fibrosis (uniform fibrosis (unlike [[UIP]]), +/-''linear fibrosis'' (fibrosis that follows alveolar walls + no architectural distortion), +/-lymphoid nodules (assoc. with collagen vascular disease), +/-focal [[organizing pneumonia]] | ||
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Clinical features (typical) of the idiopathic form:<ref name=pmid20178304>{{cite journal |author=Romagnoli M, Poletti V |title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] |language=Italian |journal=Recenti Prog Med |volume=100 |issue=12 |pages=531–4 |year=2009 |month=December |pmid=20178304 |doi= |url=}}</ref> | Clinical features (typical) of the idiopathic form:<ref name=pmid20178304>{{cite journal |author=Romagnoli M, Poletti V |title=[Update on non-specific interstitial pneumonia: a pattern, a clinical entity or different phenotypes? Surgical or bronchoscopic diagnosis?] |language=Italian |journal=Recenti Prog Med |volume=100 |issue=12 |pages=531–4 |year=2009 |month=December |pmid=20178304 |doi= |url=}}</ref> | ||
*Middle-aged, never-smoker women. | *Middle-aged, never-smoker women. | ||
*Dyspnea. | *[[Dyspnea]]. | ||
*Cough. | *Cough. | ||
*Ground glass on HRCT. | *Ground glass on HRCT. | ||
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DDx: | DDx: | ||
*[[Collagen vascular disease]]. | *[[Collagen vascular disease]]. | ||
*Drug reaction. | *[[Drug reaction]]. | ||
*[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis). | *[[Hypersensitivity pneumonitis]] (extrinic allergic alveolitis). | ||
*[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation. | *[[Lymphocytic interstitial pneumonia]] (LIP) - much more inflammation. | ||
*[[Organizing pneumonia]]. | *[[Organizing pneumonia]]. | ||
===Images=== | |||
<gallery> | |||
Image: Non-specfic_interstitial_pneumonia_(NSIP),_cellular_variant.jpg | NSIP - cellular. (WC/Rosen) | |||
Image: Non-specfic_interstitial_pneumonia_(NSIP),_cellular_variant_2.jpg | NSIP - cellular. (WC/Rosen) | |||
Image: Non-specfic interstitial pneumonia (NSIP), fibrosing variant.jpg | NSIP - fibrosing. (WC/Rosen) | |||
Image: Non-specfic interstitial pneumonia (NSIP), fibrosing variant_2.jpg | NSIP - fibrosing. (WC/Rosen) | |||
</gallery> | |||
==See also== | ==See also== | ||