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Difference between revisions of "Non-small cell lung carcinoma"
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Non-small cell lung carcinoma (view source)
Revision as of 17:01, 18 June 2017
, 17:01, 18 June 2017no edit summary
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In the clinical context, it is often referred to as '''non-small cell lung cancer'''; this ignores the fact that not all non-small cell lung cancer fits into the [[carcinoma]] category. | In the clinical context, it is often referred to as '''non-small cell lung cancer'''; this ignores the fact that not all non-small cell lung cancer fits into the [[carcinoma]] category. | ||
''Poorly differentiated carcinoma of the lung'' and ''poorly differentiated lung carcinoma'' redirect to this article. | ''Poorly differentiated carcinoma of the lung'', ''non-small cell carcinoma'' and ''poorly differentiated lung carcinoma'' redirect to this article. | ||
==General== | ==General== | ||
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*[[Malignant melanoma]]. | *[[Malignant melanoma]]. | ||
*Other poorly differentiated neoplasms | *Other poorly differentiated neoplasms | ||
===Grading=== | |||
*''NSCC-NOS'', ''NSCC favour adenocarcinoma'', ''NSCC favour SCC'' are grade 4. | |||
Note: | |||
*In a large series of patients, there is no statistical difference in survival been grade 3 and grade 4.<ref name=pmid16678584>{{Cite journal | last1 = Sun | first1 = Z. | last2 = Aubry | first2 = MC. | last3 = Deschamps | first3 = C. | last4 = Marks | first4 = RS. | last5 = Okuno | first5 = SH. | last6 = Williams | first6 = BA. | last7 = Sugimura | first7 = H. | last8 = Pankratz | first8 = VS. | last9 = Yang | first9 = P. | title = Histologic grade is an independent prognostic factor for survival in non-small cell lung cancer: an analysis of 5018 hospital- and 712 population-based cases. | journal = J Thorac Cardiovasc Surg | volume = 131 | issue = 5 | pages = 1014-20 | month = May | year = 2006 | doi = 10.1016/j.jtcvs.2005.12.057 | PMID = 16678584 }}</ref> | |||
===Images=== | ===Images=== | ||
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Note: | Note: | ||
* | *If immunostains favour adenocarcinoma or squamous cell carcinoma, the case should be sign as ''favour adenocarcinoma'' or ''favour squamous cell carcinoma'', see ''Sloan-Kettering algorithm'' below and ''Sign out'' section. | ||
===Adenocarcinoma versus squamous carcinoma=== | ===Adenocarcinoma versus squamous carcinoma=== | ||
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|- | |- | ||
| Non-small cell carcinoma, favour adenocarcinoma | | Non-small cell carcinoma, favour adenocarcinoma | ||
| TTF-1 or napsin +ve | | [[TTF-1]] or napsin +ve | ||
|- | |- | ||
| Non-small cell carcinoma, favour squamous cell carcinoma | | Non-small cell carcinoma, favour squamous cell carcinoma | ||
| p40 or p63 +ve | | [[p40]] or [[p63]] +ve | ||
|- | |- | ||
| Non-small cell carcinoma-not otherwise specified | | Non-small cell carcinoma-not otherwise specified | ||