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Difference between revisions of "Non-malignant skin disease"
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Non-malignant skin disease (view source)
Revision as of 04:42, 12 September 2011
, 04:42, 12 September 2011→Dermatomyositis: more
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==Dermatomyositis== | ==Dermatomyositis== | ||
:''For the muscle manifestations see: [[Neuromuscular_pathology#Dermatomyositis]]''. | :''For the muscle manifestations see: [[Neuromuscular_pathology#Dermatomyositis]]''. | ||
===General=== | |||
*Complement mediated disease - membrane attack complex. | |||
*Usually middle age. | |||
*Associated skin rash is common. | |||
**May precede or follow muscle pathology. | |||
*Associated with malignancy in approximately 10% of cases.<ref name=pmid20398365>{{cite journal |author=Chen YJ, Wu CY, Huang YL, Wang CB, Shen JL, Chang YT |title=Cancer risks of dermatomyositis and polymyositis: a nationwide cohort study in Taiwan |journal=Arthritis Res. Ther. |volume=12 |issue=2 |pages=R70 |year=2010 |pmid=20398365 |pmc=2888225 |doi=10.1186/ar2987 |url=}}</ref> | |||
===Gross=== | ===Gross=== | ||
*Have lesions on the | *Have lesions on the knuckles - ''Gottron's papules''. | ||
===Microsopic=== | ===Microsopic=== | ||