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Difference between revisions of "Non-malignant skin disease"
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Non-malignant skin disease (view source)
Revision as of 18:04, 28 August 2011
, 18:04, 28 August 2011→Inflammatory conditions: psoriasis
(→Very common: skin tag) |
(→Inflammatory conditions: psoriasis) |
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Features:<ref name=Ref_PBoD1065-6>{{Ref PBoD|1065-6}}</ref> | Features:<ref name=Ref_PBoD1065-6>{{Ref PBoD|1065-6}}</ref> | ||
*Subepithelial fibrosis - '''key feature'''. | *Subepithelial fibrosis - '''key feature'''. | ||
==Psoriasis== | |||
===General=== | |||
*Chronic skin condition +/- systemic involvement:<ref name=Ref_PCPBoD8_603>{{Ref PCPBoD8|603}}</ref> | |||
**[[Arthritis]]. | |||
**[[Myopathy]]. | |||
**Enteropathy, e.g. [[inflammatory bowel disease]]. | |||
**Syondylitic joint disease (spondylos = vertebrae<ref>URL: [http://medical-dictionary.thefreedictionary.com/spondylosis http://medical-dictionary.thefreedictionary.com/spondylosis]. Accessed on: 28 August 2011.</ref>). | |||
Clinical: | |||
*''Auspitz sign'' = pin-point bleeding on removal of scale. | |||
*''Koebner phenomenon'' = lesions form at site of trauma. | |||
===Microscopic=== | |||
Features:<ref name=Ref_PCPBoD8_603>{{Ref PCPBoD8|603}}</ref> | |||
*Acanthosis + long rete ridges - '''key feature'''. | |||
*Parakeratosis. | |||
*Dilated vessels in superficial dermis (give rise to ''Auspitz sign''). | |||
*Spongiform pustules = PMNs in stratum spinosum. | |||
*PMNs in parakeratotic stratum corneum (Munro microabscess). | |||
=Other= | =Other= | ||