Difference between revisions of "Non-malignant skin disease"

Non-malignant skin disease (view source)

624 bytes removed , 04:39, 28 August 2011

rm dermal nevus ---> to melanocytic lesions

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 '''Non-malignant skin disease''' is relatively common.  The pathology may or may not be specific.  Some diseases require clinical information to diagnose.
-An introduction to dermatopathology is in the ''[[dermatopathology]]'' article.
+An introduction to dermatopathology is in the ''[[dermatopathology]]'' article.  [[Nevi]] (moles) and other melanocytic lesions are dealt with in the article ''[[melanocytic lesions]]''.
 ==General classification (Inflammatory)==
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 **''Molluscum bodies'' are only the epidermis - an uncommon place to find SRCs without finding them elsewhere.
 *The granular eosinophilic cytoplasm represents accumulated virons.
-==Dermal nevus==
-*Think ''melanoma''.
-Clinical: ''ABCD'' = asymmetric, borders (irregular), colour (black), diameter (large).
-===Microscopic===
-Features:<ref>need ref</ref>
-*Symmetrical lesion.
-*"Matures" with depth - less cellular, less atypia.
-*No destruction of surrounding structures.
-*Only in dermis '''key feature'''.
-**Otherwise it is something else, e.g. ''dermal nevus'', ''junctional nevus''.
-===Microscopic===
-*Basaloid cells mixed with squamous cells.
-*Keratin-filled invaginations.
-*Horn cysts - intraepidermal, brown globule-like structures.
-**Melanocytes at the dermoepidermal junction.<ref>[http://emedicine.medscape.com/article/1059477-overview http://emedicine.medscape.com/article/1059477-overview]</ref>
 ==Pilomatricoma==